Remission rates, time to remission, and related factors in adolescents with major depressive disorder

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dc.authorid0000-0001-8397-5636en_US
dc.authorid0000-0002-3412-9879en_US
dc.authorid0000-0002-4322-7251en_US
dc.authorid0000-0001-8196-6664en_US
dc.authorid0000-0002-4130-0494en_US
dc.authorid0000-0001-5207-6240en_US
dc.contributor.authorTopal, Zehra
dc.contributor.authorÖztürk, Yusuf
dc.contributor.authorDemir, Nuran
dc.contributor.authorAdıgüzel, Öznur
dc.contributor.authorKaradağ, Mehmet
dc.contributor.authorTufan, Ali Evren
dc.date.accessioned2023-06-19T11:40:59Z
dc.date.available2023-06-19T11:40:59Z
dc.date.issued2021en_US
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective: Major depressive disorder (MDD) is a common disorder in children and adolescents that can cause serious morbidity and mortality. Although response rates to treatment are high, less than half of the adolescents with MDD achieve remission. The present study aims to evaluate remission rates, time to remission, and the predictors of remission in adolescents with MDD. Methods: This study included 34 adolescents with MDD who were followed-up for a minimum period of 120days. The adolescents were assessed with the Clinic Global Impression Scale, Beck Depression Inventory, Young Mania Rating Scale, Child Mania Rating Scale, and Screen for Child Anxiety-Related Emotional Disorders at the baseline and at weeks 4, 8, and 12. Results: 67.6% of the adolescents had at least one comorbid diagnosis. The remission rate at week 12 was 735%. The mean time to remission was 72.0days. The female adolescents achieved a significantly higher remission rate than the males. Conclusion: The majority of adolescents achieved remission following acute treatment, and that the time to remission for the female adolescents was shorter compared with the males. Remission time does seem neither to be related to the number of medications prescribed nor to the number of comorbid diagnoses.en_US
dc.identifier.citationTopal, Z., Öztürk, Y., Demir, N., Adıgüzel, O., Karadag, M., & Tufan, A. E. (2021). Remission Rates, Time to Remission, and Related Factors in Adolescents with Major Depressive Disorder. European Journal of Therapeutics, 27(3), 219-223.en_US
dc.identifier.doi10.5152/eurjther.2021.20081Original Article219
dc.identifier.endpage223en_US
dc.identifier.issn2564-7040
dc.identifier.issue3en_US
dc.identifier.startpage219en_US
dc.identifier.trdizinid476348en_US
dc.identifier.urihttp://dx.doi.org/10.5152/eurjther.2021.20081
dc.identifier.urihttps://hdl.handle.net/20.500.12491/11142
dc.identifier.volume27en_US
dc.identifier.wosWOS:000703346900007en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorÖztürk, Yusuf
dc.language.isoenen_US
dc.publisherAvesen_US
dc.relation.ispartofEuropean Journal of Therapeuticsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAdolescent Depressionen_US
dc.subjectTreatment Outcomesen_US
dc.subjectRemissionen_US
dc.titleRemission rates, time to remission, and related factors in adolescents with major depressive disorderen_US
dc.typeArticleen_US

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