SPR signal enhancement with silver nanoparticle-assisted plasmonic sensor for selective adenosine detection
Yükleniyor...
Dosyalar
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
IEEE-Inst Electrical Electronics Engineers Inc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study, we fabricated adenosine imprinted poly(hydroxyethyl methacrylate-N-methacryloyl-L-cysteine methyl ester-silver nanoparticles (AgNPs)-N-methacryloyl-L-phenylalanine methyl ester) (MIP-Ag) sensor. It is a sensitive, simple, low-cost, and label-free adenosine determination in an aqueous solution without the need for any complicated coupling processes. The sensor without the addition of AgNPs (MIP) was prepared for control experiments to examine the effect of incorporated AgNPs to increase the signal response of surface plasmon resonance. Also, non-imprinted (NIP-Ag) sensor were designed using the same polymerization recipe without adding adenosine to evaluate the imprinting efficiency. The characterization studies of MIP-Ag, NIP-Ag and MIP sensors were carried out by atomic force microscopy and contact angle measurements. It was determined that the MIP-Ag sensor detected the target adenosine molecule 5.10 times more selectively than the competitor guanosine and 3.92 times more than thymidine. Imprinting efficiency was determined by comparing the signal response of MIP-Ag and NIP-Ag sensors. Repeatability studies of the MIP-Ag sensor were statistically analyzed for the 1.0 ppm adenosine, and the percent relative standard deviation of the intraday assays of less than 1.0% showed an insignificant decrease in the detection of adenosine after four adsorption-desorption cycles.
Açıklama
Anahtar Kelimeler
Sensor Phenomena and Characterization, Polymers, Size Measurement, Image Sensors, Sensor Systems, Silver
Kaynak
IEEE Sensors Journal
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
22
Sayı
15
Künye
Göktürk, I., Bakhshpour, M., Çimen, D., Yılmaz, F., Bereli, N., & Denizli, A. (2022). SPR Signal Enhancement With Silver Nanoparticle-Assisted Plasmonic Sensor for Selective Adenosine Detection. IEEE Sensors Journal, 22(15), 14862-14869.
