Effects of bispectral index-controlled use of magnesium on propofol consumption and sedation level in patients undergoing colonoscopy

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dc.authorid0000-0002-9265-1008
dc.authorid0000-0001-7476-2217
dc.authorid0000-0003-2954-4784
dc.authorid0000-0002-1571-6920
dc.authorid0000-0001-5524-5767
dc.authorid0000-0003-4139-5080
dc.authorid0000-0002-9001-2309
dc.contributor.authorYoldaş, Hamit
dc.contributor.authorYıldız, İsa
dc.contributor.authorKaragöz, İbrahim
dc.contributor.authorDemirhan, Abdullah
dc.contributor.authorBilgi, Murat
dc.contributor.authorŞit, Mustafa
dc.contributor.authorOgün, Muhammed Nur
dc.date.accessioned2021-06-23T18:34:06Z
dc.date.available2021-06-23T18:34:06Z
dc.date.issued2019
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective: The aim of this study is to investigate the effects of bispectral index-controlled use of magnesium on propofol consumption, periprocedural hemodynamic response and patient comfort.Material: A total of 60 patients were enrolled in the study. In Group 1 (magnesium), a single dose 50 mg/kg magnesium sulfate diluted with 100 mL 0.9% NaCl was administered 10 min-utes before the beginning of the procedure. Initially bolus dose of 0.5 mg/kg propofol was ap-plied. The maintenance dose of propofol was 60 mcg/kg/min. During the procedure, the propo-fol infusion was increased by titration until the bispectral index (BIS) value of 70 was achieved. In Group 2 (saline), 100 ml 0.9% NaCl was administered 10 minutes before the beginning of the procedure. The bolus and maintenance doses of propofol, and target BIS values were the same as those in Group 1.Results: When BIS values were compared between the groups, the initial BIS values in the magnesium group (Group 1) were significantly higher than those of the saline group (Group 2) (p<0.05). The time to reach BIS 70 was significantly shorter in the magnesium group (p<0.05). Propofol consumption was greater in Group 2 than in Group 1 (p<0.05). The time to reach BIS 70 was significantly shorter in Group 1 (p<0.05). No significant difference was found between the groups in terms of patient- and endoscopist-satisfaction (p<0.05).Conclusion: The use of magnesium in addition to propofol may be an efficient and reliable op-tion to reduce the drug consumption during colonoscopic interventions.en_US
dc.identifier.doi10.5222/MMJ.2019.99705
dc.identifier.endpage386en_US
dc.identifier.issn2149-2042
dc.identifier.issn2149-4606
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85077549530en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage380en_US
dc.identifier.trdizinid383700en_US
dc.identifier.urihttps://doi.org/10.5222/MMJ.2019.99705
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TXpnek56QXdNQT09
dc.identifier.urihttps://hdl.handle.net/20.500.12491/2414
dc.identifier.volume34en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorYoldaş, Hamit
dc.institutionauthorYıldız, İsa
dc.institutionauthorKaragöz, İbrahim
dc.institutionauthorDemirhan, Abdullah
dc.institutionauthorBilgi, Murat
dc.institutionauthorŞit, Mustafa
dc.institutionauthorOgün, Muhammed Nur
dc.language.isoenen_US
dc.relation.ispartofMedeniyet Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBispectral Index
dc.subjectColonoscopy
dc.subjectMagnesium
dc.subjectBispektral İndeks
dc.subjectKolonoskopi
dc.subjectMagnezyum
dc.titleEffects of bispectral index-controlled use of magnesium on propofol consumption and sedation level in patients undergoing colonoscopyen_US
dc.typeArticleen_US

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