Poly(vinyl alcohol)/polyethyleneimine (PVA/PEI) blended monolithic cryogel columns for the depletion of haemoglobin from human blood

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dc.authoridGOKTURK, ILGIM/0000-0001-7292-7241
dc.contributor.authorGokturk, Ilgim
dc.contributor.authorDerazshamshir, Ali
dc.contributor.authorYilmaz, Fatma
dc.contributor.authorDenizli, Adil
dc.date.accessioned2024-09-25T19:57:36Z
dc.date.available2024-09-25T19:57:36Z
dc.date.issued2016
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractWe have synthesized PVA/PEI monolithic cryogel columns chelated with Cu2+ ions as a model adsorbent, which is capable of binding haemoglobin (Hb) from human blood. The goal of this study is to perform the depletion of Hb via a single and easy process to be useful in proteomic studies. PVA/PEI-Cu2+ cryogel columns were subjected to adsorption studies of Hb from both aqueous solution and human plasma to evaluate the extent of interaction between cryogel columns and Hb. The effects of experimental parameters, such as pH, Hb equilibrium concentration, adsorption time, temperature, and ionic strength, on Hb adsorption capacity were investigated.en_US
dc.identifier.doi10.1080/01496395.2016.1183677
dc.identifier.endpage1797en_US
dc.identifier.issn0149-6395
dc.identifier.issn1520-5754
dc.identifier.issue11en_US
dc.identifier.startpage1787en_US
dc.identifier.urihttps://doi.org/10.1080/01496395.2016.1183677
dc.identifier.urihttps://hdl.handle.net/20.500.12491/13481
dc.identifier.volume51en_US
dc.identifier.wosWOS:000381286400002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofSeparation Science And Technologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzYK_20240925en_US
dc.subjectCryogelen_US
dc.subjecthaemoglobinen_US
dc.subjectIMACen_US
dc.subjectPEI-Cu2+en_US
dc.subjectPVAen_US
dc.titlePoly(vinyl alcohol)/polyethyleneimine (PVA/PEI) blended monolithic cryogel columns for the depletion of haemoglobin from human blooden_US
dc.typeArticleen_US

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