Efficacy of throat gargling for detection of group a beta-hemolytic streptococcus

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dc.authoridKarabay, Oguz/0000-0003-0502-432X
dc.authoridKARABAY, OGUZ/0000-0003-1514-1685
dc.contributor.authorKarabay, O
dc.contributor.authorEkerbicer, H
dc.contributor.authorYilmaz, F
dc.date.accessioned2024-09-25T20:01:44Z
dc.date.available2024-09-25T20:01:44Z
dc.date.issued2005
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractThe purpose of our study was to investigate the suitability of throat gargling with sterile saline as an alternative method to throat swabs for detection of group A beta-hemolytic streptococcus (GAS). Throat specimens were obtained from 601 cases belonging to different age groups. Sterile Dacron swabs and gargle residue were first streaked on the side of a 5% sheep blood agar plate to which a 0.04 U bacitracin disk bad been applied, and then 1.25 mg trimethoprim and 23.75 mg sulphamethoxazole were added to the plate. After incubation, beta-hemolytic colonies were classified serologically by latex agglutination. GAS was detected in both throat swabs and throat gargle specimens in 49 cases, but GAS was also detected in 12 throat swabs from patients with culture-negative gargles and in 8 gargle specimens from subjects in whom throat swabs were culture negative. The strength of agreement was evaluated by calculating the kappa coefficient (K = 0.82, P = 0.000). The sensitivity, specificity, positive predictive value, and negative predictive value of throat gargle specimens were 80.3, 98.5, 85.9, and 97.8%, respectively. Although the conventional throat swab culture remains the gold standard, the throat gargle method is a quick, safe, and easy method for detection of GAS that serves as an effective alternative to throat swab culture.en_US
dc.identifier.endpage40en_US
dc.identifier.issn1344-6304
dc.identifier.issn1884-2836
dc.identifier.issue1en_US
dc.identifier.pmid15728991en_US
dc.identifier.startpage39en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/14300
dc.identifier.volume58en_US
dc.identifier.wosWOS:000227398900011en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherNatl Inst Infectious Diseasesen_US
dc.relation.ispartofJapanese Journal of Infectious Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzYK_20240925en_US
dc.titleEfficacy of throat gargling for detection of group a beta-hemolytic streptococcusen_US
dc.typeArticleen_US

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