High sensitivity C-reactive protein levels in chronic rhinosinusitis and allergic rhinitis
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Tarih
2011
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Bu çalışmada alerjik rinitli, nazal polipli ve polipsiz kronik rinosinüzitli (KRS) hastaların periferik kanlarındaki yüksek duyarlılıklı C-reaktif protein (hs-CRP) düzeyleri arasındaki ilişki değerlendirildi. Hastalar ve Yöntemler: Çalışmaya dahil edilen 100 hasta; alerjik rinitli hastalar (grup 1), nazal polipli KRS’li hastalar (grup 2), nazal polipsiz KRS’li hastalar (grup 3) ve sigara içmeyen kontroller (grup 4) olmak üzere 25’er kişilik dört gruba ayrıldı. Tüm hastalara detaylı semptom sorgulaması, fizik muayene, tam kan sayımı ve paranazal sinüs radyografileri yapıldı. Tüm hastalarda hs-CRP düzeyleri semi kantitatif olarak, lateks ile güçlendirilmiş immünonefelometrik yöntem ile ölçüldü. Bulgular: Yüksek duyarlılıklı-CRP düzeyleri açısından grup 1, grup 2 ve grup 3 ile kontrol grubu arasında istatistiksel olarak anlamlı farklılık yoktu (sırasıyla; p=0.861, p=0.7196 ve p=0.127). Sonuç: Alerjik rinit, nazal polipli KRS ve nazal polipsiz KRS gruplarında periferik kan hs-CRP düzeyleri kontrol grubu ile karşılaştırıldığında istatistiksel anlamlı farklılık saptanmadı.
Objectives: In this study we evaluated the relationship between peripheral blood high sensitivity C-reactive protein (hs-CRP) levels with allergic rhinitis and chronic rhinosinusitis (CRS) with or without nasal polyps. Patients and Methods: The study included 100 patients who were divided into four groups each 25 patients; as follows: allergic rhinitis (group 1), CRS with nasal polyps (group 2), CRS without nasal polyps (group 3), and controls (group 4) who were non-smokers. All patients underwent a detailed symptom enquiry, physical examination, and investigations including a complete blood count and radiograph of the paranasal sinuses. The hs-CRP was measured in all the patients by a semi quantitative assay using the latex enhanced immunonephelometric test. Results: There was no statistically significant difference in the levels of hs-CRP between the group 1, group 2, and group 3 by the control group respectively (p=0.861, p=0.7196, and p=0.127). Conclusion: Allergic rhinitis, CRS with nasal polyps and CRS without nasal polyp groups compared with the control group were statistically not significant differences in the hs-CRP levels with peripheral blood.
Objectives: In this study we evaluated the relationship between peripheral blood high sensitivity C-reactive protein (hs-CRP) levels with allergic rhinitis and chronic rhinosinusitis (CRS) with or without nasal polyps. Patients and Methods: The study included 100 patients who were divided into four groups each 25 patients; as follows: allergic rhinitis (group 1), CRS with nasal polyps (group 2), CRS without nasal polyps (group 3), and controls (group 4) who were non-smokers. All patients underwent a detailed symptom enquiry, physical examination, and investigations including a complete blood count and radiograph of the paranasal sinuses. The hs-CRP was measured in all the patients by a semi quantitative assay using the latex enhanced immunonephelometric test. Results: There was no statistically significant difference in the levels of hs-CRP between the group 1, group 2, and group 3 by the control group respectively (p=0.861, p=0.7196, and p=0.127). Conclusion: Allergic rhinitis, CRS with nasal polyps and CRS without nasal polyp groups compared with the control group were statistically not significant differences in the hs-CRP levels with peripheral blood.
Açıklama
Anahtar Kelimeler
Allergic Rhinitis, Chronic Rhinosinusitis, High Sensitivity-C-Reactive Protein, Nasal Polyp, Alerjik Rinit, Kronik Rinosinüzit, Yüksek Duyarlılıklı-C-Reaktif Protein, Nazal Polip
Kaynak
Kulak Burun Boğaz İhtisas Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
21
Sayı
5