C-reactive protein to LymphocytE count ratio could be a reliable marker of thyroiditis; the CLEAR-T study

Basit Öğe Kaydı
dc.authorid0000-0001-6262-6103en_US
dc.authorid0000-0001-7306-5233en_US
dc.contributor.authorDemirkol, Muhammed Emin
dc.contributor.authorAktaş, Gülali
dc.date.accessioned2023-07-27T05:21:18Z
dc.date.available2023-07-27T05:21:18Z
dc.date.issued2022en_US
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractInflammation of the thyroid gland is referred to as thyroiditis and is associated with inflammation. Recent studies found significant association between thyroiditis and novel inflammatory and metabolic markers, as well as C-reactive protein (CRP). CRP/lymphocyte count ratio (CLR) is a novel inflammatory marker that associated with various conditions and has not been studied in thyroiditis, yet. We aimed to investigate CRP to lymphocyte count ratio in patients with thyroiditis and to compare to those in healthy subjects. Patients with thyroiditis that presented to internal medicine outpatient clinics of our institution between January 2019 and August 2021 were enrolled to the retrospective study. Healthy volunteers were enrolled as control group. CLR of the thyroiditis and control groups were compared. Median CLR of the thyroiditis and control groups were 3.14 (0.14%-38)% and 0.4 (0.03-8.86)%, respectively (p < .001). The sensitivity and specificity of CLR > 0.43% in detecting thyroiditis were 92% and 58%, respectively (AUC: 0.88, p < .001, 95% CI: 0.85-0.92).CLR was significantly and positively correlated with free T4 (FT4) (r = .18, p < .001) and inversely correlated with thyroid stimulating hormone (TSH) (r = -.52, p = .003) levels. In conclusion, we suggest that high CLR levels may yield additional diagnostic value in patients with thyroiditis.en_US
dc.identifier.citationDemirkol, M. E., & Aktas, G. (2022). C‐reactive protein to LymphocytE count ratio could be a reliable mArkeR of thyroiditis; the CLEAR‐T study. Precision Medical Sciences, 11(1), 31-34.en_US
dc.identifier.doi10.1002/prm2.12065
dc.identifier.endpage34en_US
dc.identifier.issn2642-2514
dc.identifier.issue1en_US
dc.identifier.startpage31en_US
dc.identifier.urihttp://dx.doi.org/10.1002/prm2.12065
dc.identifier.urihttps://hdl.handle.net/20.500.12491/11371
dc.identifier.volume11en_US
dc.identifier.wosWOS:000804537900001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.institutionauthorDemirkol, Muhammed Emin
dc.institutionauthorAktaş, Gülali
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofPrecision Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectC-Reactive Proteinen_US
dc.subjectLymphocyte Count Ratioen_US
dc.subjectInflammationen_US
dc.subjectThyroiditisen_US
dc.subjectLymphopeniaen_US
dc.subjectThyroid Glanden_US
dc.titleC-reactive protein to LymphocytE count ratio could be a reliable marker of thyroiditis; the CLEAR-T studyen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
muhammed-emin-demirkol (2).pdf
Boyut:
615.9 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam metin/Full text
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Dahili Tıp Bilimleri Bölümü Koleksiyonu