Physico-chemical properties of DNA in phylogeny construction

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dc.contributor.authorBakış, Yasin
dc.contributor.authorSezerman, Osman Uğur
dc.contributor.authorOtu, Hasan H.
dc.date.accessioned2021-06-23T18:51:54Z
dc.date.available2021-06-23T18:51:54Z
dc.date.issued2010
dc.departmentBAİBÜ, Fen Edebiyat Fakültesi, Biyoloji Bölümüen_US
dc.descriptionMiddle East Technical University;Institute of Electrical and Electronics Engineers (IEEE);Turkey Sectionen_US
dc.description2010 5th International Symposium on Health Informatics and Bioinformatics, HIBIT 2010 -- 20 April 2010 through 22 April 2010 -- Antalya -- 81058en_US
dc.description.abstractPhylogenic analysis relies on alignment of related sequences from different species to obtain the distances between these species. The quality of the alignment and the distance measure would depend on the alignment parameters that are used. In this work, we propose to use Relative Complexity Measure (RCM) to find the distances between the sequences which is not a parameter dependent measure. We used DNA sequences from Candida species and phylogenetic trees were obtained using un-weighted pair-group with arithmetic mean method. We used three reduced alphabets for the DNA sequences which were clustered by taking into account different physicochemical properties of DNA. RCM gives as good results as the distance determination method and among the physicochemical properties, Keto/Amino grouping is found to give the most accurate tree which is topological closest to the desired phylogeny. ©2009 IEEE.en_US
dc.description.urihttps://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=5478912
dc.identifier.doi10.1109/HIBIT.2010.5478912
dc.identifier.endpage30en_US
dc.identifier.isbn9781424459704
dc.identifier.scopus2-s2.0-77954497977en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage27en_US
dc.identifier.urihttps://doi.org/10.1109/HIBIT.2010.5478912
dc.identifier.urihttps://hdl.handle.net/20.500.12491/4052
dc.indekslendigikaynakScopusen_US
dc.institutionauthorBakış, Yasin
dc.language.isoenen_US
dc.relation.ispartof2010 5th International Symposium on Health Informatics and Bioinformatics, HIBIT 2010en_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCandidaen_US
dc.subjectDNAen_US
dc.subjectPhylogeneticsen_US
dc.subjectPhysico-chemical propertiesen_US
dc.subjectReduced alphabetsen_US
dc.subjectRelative complexity measureen_US
dc.titlePhysico-chemical properties of DNA in phylogeny constructionen_US
dc.typeConference Objecten_US

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