Comparison of demographical properties, Biochemical Parameters, Flow-mediated dilatation values and Carotis Intima Media Thickness of patients with Coronary Artery disease

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dc.authorid0000-0002-3893-5376
dc.authorid0000-0001-9532-8241
dc.authorid0000-0003-1784-3584
dc.authorid0000-0002-1168-0940
dc.contributor.authorErdal, Emrah
dc.contributor.authorGürler, Müjgan
dc.contributor.authorİnanır, Mehmet
dc.contributor.authorÖzmen, Namık
dc.date.accessioned2021-06-23T18:26:14Z
dc.date.available2021-06-23T18:26:14Z
dc.date.issued2020
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractTo compare demographic characteristics, biochemical parameters, flow-mediated dilatation (FMD) values and carotid intima-media thickness (CIMT) between older (>45 years) and younger (<45 years) patients with coronary artery disease (CAD). Materials and Methods: The present study comprised a total of 114 patients divided into four groups. For the study groups, group 1 had 30 patients with CAD <45 years of age, and group 2 had 32 patients with CAD >45 years of age. Group 3 and group 4 were used as controls, comprising 28 (<45 years) and 24 (>45 years) healthy participants, respectively. Demographic characteristics, biochemical parameters, FMD values and CIMT were recorded and compared statistically among patients. Results: The median age of patients was 47.81±14.50 years. Hereditary risk factors and hyperlipidemia were statistically significant in group 1 than those in group 3. Likewise, fasting blood glucose levels and CIMT values were statistically higher in group 1 than those in group 3. Gender distribution and hyperlipidemia were statistically significant in group 2, in contrast to those in group 4. The values of FMD was lower in group 2 than those in group 4, which seemed to be statistically significant. The values of CIMT were higher whereas platelet counts were lower in group 2 than those in group 1, both findings of which were also statistically significant. The values of CIMT and Neutrophil/Lymphocyte (N/L) ratios increased whereas the values of FMD decreased significantly as the ages of participants increased. Conclusion: The factors where CAD was more common in subjects were as follows: being over 45 years of age (2.36 times), the presence of hyperlipidemia (3.58 times), increased N/L ratios (1.6 times), a combination of increased CIMT values and age (12 times), and decreased FMD values (2 times).en_US
dc.identifier.doi10.32596/ejcm.galenos.2020.01.03
dc.identifier.endpage137en_US
dc.identifier.issn2147-1924
dc.identifier.issue3en_US
dc.identifier.startpage131en_US
dc.identifier.trdizinid378826en_US
dc.identifier.urihttps://doi.org/10.32596/ejcm.galenos.2020.01.03
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TXpjNE9ESTJOZz09
dc.identifier.urihttps://hdl.handle.net/20.500.12491/1418
dc.identifier.volume8en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorErdal, Emrah
dc.institutionauthorGürler, Müjgan
dc.institutionauthorİnanır, Mehmet
dc.language.isoenen_US
dc.relation.ispartofE Journal of Cardiovascular Medicineen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCarotid Intima-Media Thicknessen_US
dc.subjectCoronary Artery Disease
dc.subjectEndothelial Dysfunction
dc.subjectFlow-Mediated Dilatation Values
dc.titleComparison of demographical properties, Biochemical Parameters, Flow-mediated dilatation values and Carotis Intima Media Thickness of patients with Coronary Artery diseaseen_US
dc.typeArticleen_US

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