Base-promoted new C-C bond formation: an expedient route for the preparation of thiazolo- and imidazolo-pyridinones via Michael addition
Yükleniyor...
Dosyalar
Tarih
2014
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Pergamon-Elsevier Science Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Base-catalyzed one-pot cyclocondensation reactions of acryloyl and cinnamoyl chlorides with beta-nitroenamine derivatives have been performed under mild conditions and target 7-substituted thiazolo-[3,2-alpha] or imidazolo-[1,2-alpha]pyridin-5-one derivatives were prepared successfully in moderate to good yields. The cyclization reactions may proceed via Michael addition followed by iminoketene-amide tautomerization in view of the products formed. (C) 2014 Elsevier Ltd. All rights reserved.
Açıklama
Anahtar Kelimeler
Heterocyclic Nitroenamine, One-pot Reaction, Multicomponent, Michael Addition, Cinnamoyl Chlorides
Kaynak
Tetrahedron
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
70
Sayı
35
