Küçük hücreli akciğer kanseri olgusunda tümör lizis sendromu

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dc.authorid0000-0003-2213-5881
dc.contributor.authorArbak, Peri
dc.contributor.authorBilgin, Cahit
dc.contributor.authorBalbay, Öner
dc.contributor.authorBicik, Zerrin
dc.date.accessioned2024-09-25T19:59:59Z
dc.date.available2024-09-25T19:59:59Z
dc.date.issued2005
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü en_US
dc.description.abstractAs a result of large tumor burden, acute tumor lysis syndrome (TLS) is most often seen with lymphoproliferative disorders. An uncommon association of solid tumors and TLS also have been reported. We present a patient with metastatic lung carcinoma who developed TLS. A 58-year-old male was hospitalized for a mass in left lower lobe of lung and multiple low attenuation lesions in liver revealed by computed tomography. Liver biopsy specimen revealed metastatic small cell lung carcinoma. Cisplatin (60 mg/m(2), day1), Etoposide (120 mg/m(2), day 1,2,3) regimen was started. Biochemical parameters of the patient were in normal ranges before chemotherapy, one and two days after chemotherapy. At the seventh day of discharge from the hospital, our patient admitted to emergency department with acute renal insufficiency. Patient was recruited to hemodialysis for TLS. After 3 cycles of hemodialysis biochemical parameters were normalized. Since then etoposide regimen (100 mg/day for 14 days/monthly) was used. After 4 cycles of oral Etoposide regimen symptomatic relief and incomplete response according to chest radiograph were observed. Our case was presented with a later occurence of TLS when compared with the other cases from literature. We concluded that especially in disseminated small cell lung cancer (SCLC), clinicians must be aware of this rare but fatal complication.en_US
dc.identifier.endpage126en_US
dc.identifier.issn2148-3620
dc.identifier.issn2148-5402
dc.identifier.issue3en_US
dc.identifier.startpage123en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/14023
dc.identifier.volume7en_US
dc.identifier.wosWOS:000216557300005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.institutionauthorBilgin, Cahit
dc.institutionauthorid0000-0003-2213-5881
dc.language.isotren_US
dc.publisherAvesen_US
dc.relation.ispartofEurasian Journal of Pulmonologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzYK_20240925en_US
dc.subjectSmall Cell Lung Cancer (SCLC)en_US
dc.subjectTumor Lysis Syndrome (TLS)en_US
dc.subjectBiochemical Parameters
dc.subjectLiver Biopsy
dc.subjectAcute Renal Insufficiency
dc.titleKüçük hücreli akciğer kanseri olgusunda tümör lizis sendromu
dc.title.alternativeAcute tumor lysis syndrome in a small cell lung cancer case
dc.typeArticleen_US

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