Impact of opium use on the conventional coronary artery risk factors among outpatients in Afghanistan: A case-control study in Andkhoy city

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dc.authorid0000-0003-1758-8341en_US
dc.contributor.authorHamrah, Mohammad Shoaib
dc.contributor.authorHamrah, Mohammad Hassan
dc.contributor.authorHamrah, Mohammad Hussain
dc.contributor.authorDahi, Toba
dc.contributor.authorHamrah, Ahamad Tareq
dc.date.accessioned2023-07-18T08:34:56Z
dc.date.available2023-07-18T08:34:56Z
dc.date.issued2021en_US
dc.departmentBAİBÜ, Diş Hekimliği Fakültesi, Periodontoloji Ana Bilim Dalıen_US
dc.descriptionAcknowledgement: Our study project was supported by the Terumo Foundation for Life Science and Art. The authors are grateful to Ms. Terri Stevens for proof reading of the manuscript.en_US
dc.description.abstractBackground: According to a recent study, opium use like other risk factors, is considered an independent risk factor for Coronary Artery Disease (CAD). Its association with other risk factors increases the risk of CAD. However, debate continues about this association. Aim: To explore the association between the conventional CAD risk factors and opium use among patients visiting an outpatient clinic in Andkhoy, Afghanistan. Methods: The case-control study was performed on 574 patients aged 18 years and above including 161 opium addicts and (case group) and 413 non-addicts (control group) from October 2017 to April 2018. Results: There were 277 males (48.3%) and 297 females (51.7%). The mean age was 53.2 (+/- 13.1) for opium users and 53.9 (+/- 13.5) for non-opium users. Opium use was associated with male gender (OR=8.2, 95% CI: 4.2-16.0), smoking (OR=9.0, 95% CI: 4.7-17.3), decreased Fasting Blood Sugar (FBS) levels (OR=1.0, 95% CI: 1.0-1.1), decreased total cholesterol levels (OR=3.4, 95% CI:1.8-6.2), physical inactivity (OR=3.9, 95% CI: 2.1-7.2), and hypertension (OR=15.1 95% CI: 6.7-33.8). Conclusions: We found that the opium use was associated with male gender, smoking, hypertension, decreased total serum cholesterol levels and decreased FBS levels. However, the association between opium use and the decreased total serum cholesterol levels and decreased FBS levels may be due to short-term hormonal and neural effects. Therefore, it should be advised not use opium as a cardioprotective agent.en_US
dc.description.sponsorshipTerumo Foundation for Life Science and Arten_US
dc.identifier.citationHamrah, M. S., Hamrah, M. H., Hamrah, M. H., Dahi, T. O. B. A., Hamrah, A. T., Zarghami, F. A. T. E. M. E. H., ... & HAMRAH, M. H. (2021). Impact of opium use on the conventional coronary artery risk factors among outpatients in Afghanistan: A case-control study In Andkhoy City. Pak. J. Med. Health Sci, 15(1), 461-467.en_US
dc.identifier.endpage467en_US
dc.identifier.issn1996-7195
dc.identifier.issue1en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage461en_US
dc.identifier.urihttps://www.webofscience.com/wos/woscc/full-record/WOS:000646237300082
dc.identifier.urihttps://hdl.handle.net/20.500.12491/11308
dc.identifier.volume15en_US
dc.identifier.wosWOS:000646237300082en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorDahi, Toba
dc.language.isoenen_US
dc.publisherLahore Medical & Dental Collen_US
dc.relation.ispartofPakistan Journal of Medical & Health Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - İdari Personel ve Öğrencien_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCADen_US
dc.subjectOpium Useen_US
dc.subjectRisk Factorsen_US
dc.subjectGlucose-Metabolismen_US
dc.subjectAlcohol-Useen_US
dc.subjectDrug-Useen_US
dc.titleImpact of opium use on the conventional coronary artery risk factors among outpatients in Afghanistan: A case-control study in Andkhoy cityen_US
dc.typeArticleen_US

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