Halkımızda abdominal obezitede risk faktörü kümelenmeleri ve demografik dağılımı
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Dosyalar
Tarih
2005
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Türk erişkinlerinde abdominal obezitenin yaş gruplarına ve coğrafi bölgelerimize göre dağılımı; abdominal obezitenin yüksek total ve düşük HDL kolesterol düzeyleri, sigara içimi, hipertansiyon ve diyabet gibi başlıca risk faktörleriyle kümelenme sıklığı ve tipleri araştırıldı. Çalışma planı: Çalışmaya, Türk Erişkinlerinde Kalp Hastalığı ve Risk Faktörleri (TEKHARF) çalışmasının son üç taramasında bel çevresi ölçülmüş olan 3267 kişi (1607 erkek, 1660 kadın; ort. yaş 52±12) alındı. Kardioyovasküler hastalık tanısı anamnezde angina varlığı, istirahat elektrokardiyografisinin Minnesota kodlamasına ve inme öyküsüne dayanılarak kondu. NCEP ATP III tarafından metabolik sendrom çerçevesinde önerilen bel çevresi ölçütlerine ve hipertansiyon tanımına uyuldu. Bulgular: Elli yaş ve üzerindeki her dört erkekten biri, her dört kadından üçü abdominal obeziteli bulundu. Abdominal obezite prevalansı bölgelerimize göre büyük farklılıklar sergilemedi. Abdominal obezitelilerde 3-5 risk faktörünün birlikteliği diğer kümelenmelere göre daha fazlaydı (p<0.001). İncelenen altı risk faktörü de kadında abdominal obeziteyle anlamlı bağımsız ilişki gösterirken, erkekte yalnız sigara, HDL-kolesterol düşüklüğü ve hipertansiyon bağımsız ilişki sergiledi. Erkeklerden farklı olarak, kadınlarda diyabet abdominal obeziteye üç kattan fazla eşlik etmekte ve bu ikisi hiperkolesterolemi ile anlamlı derecede fazla kümeleşmekteydi. Abdominal obezite, kadında koroner kalp hastalığı olasılığını diğer beş risk faktörü aracılığıyla belirlerken, erkekte anılan etmenlerin dışında bağımsız bir belirleyici niteliğine sahipti. Sonuç: Batıda türetilmiş ölçütler kullanıldığında, abdominal obezite Türk kadınında erkeğe kıyasla üç kat daha sık görülmektedir. Cinsiyete özgü önemli bir farkı açığa vuran abdominal obezite-diyabet-hiperkolesterolemi kombinasyonu Türk kadınındaki yüksek koroner kalp hastalığı riskine muhtemelen katkıda bulunmaktadır. Buna benzer bir çalışmanın Türk erkeği için daha önce önerdiğimiz ≥96 cm ölçütüyle tekrarlanmasında yarar vardır.
Objectives: We investigated the distribution of abdominal obesity among Turkish adults, according to age groups and geographic regions, and the prevalence and type of its clustering with traditional risk factors including high total and low HDL cholesterol levels, smoking, hypertension, and diabetes. Study design: The study included a cohort of 3267 individuals (1607 men, 1660 women; mean age 52±12 years) whose waist circumferences were measured at least one time in the past three sur veys of the Turkish Adult Risk Factor Study from 2000 to 2004. Cardiovascular disease was diagnosed on the basis of the presence of angina history, the Minnesota coding of resting electrocardiograms, and a history of stroke. Criteria of the NCEP ATP III guidelines proposed for metabolic syndrome were adopted for defining abdominal obesity and hypertension. Results: Out of every four adults aged 50 years or above, one man and three women had abdominal obesity. The prevalence of abdominal obesity did not exhibit marked changes among geographic regions. Coexistence of 3-5 risk factors in subjects with abdominal obesity showed a significantly higher proportion than other clusters of risk factors (p<0.001). All of the six risk factors studied exhibited significant and independent associations with abdominal obesity in women, whereas in men, only smoking, low HDL-C levels, and hypertension were independent factors. In contradistinction to men, there was an over three-fold adjusted likelihood of diabetes to accompany abdominal obesity in women, with hypercholesterolemia significantly clustering with both. While abdominal obesity conferred an increased likelihood of coronary heart disease through mediation of five risk factors in women, it was found as a residual independent component in men. Conclusion: According to the NCEP ATP III criteria, abdominal obesity is three times more prevalent among Turkish women than in men. The female-specific combination of abdominal obesity, diabetes, and hypercholesterolemia may partly contribute to the comparatively high risk for cardiovascular disease in Turkish women. This study needs a re-evaluation of the role of abdominal obesity in Turkish men with a threshold of ≥96 cm, which was previously proposed by the authors.
Objectives: We investigated the distribution of abdominal obesity among Turkish adults, according to age groups and geographic regions, and the prevalence and type of its clustering with traditional risk factors including high total and low HDL cholesterol levels, smoking, hypertension, and diabetes. Study design: The study included a cohort of 3267 individuals (1607 men, 1660 women; mean age 52±12 years) whose waist circumferences were measured at least one time in the past three sur veys of the Turkish Adult Risk Factor Study from 2000 to 2004. Cardiovascular disease was diagnosed on the basis of the presence of angina history, the Minnesota coding of resting electrocardiograms, and a history of stroke. Criteria of the NCEP ATP III guidelines proposed for metabolic syndrome were adopted for defining abdominal obesity and hypertension. Results: Out of every four adults aged 50 years or above, one man and three women had abdominal obesity. The prevalence of abdominal obesity did not exhibit marked changes among geographic regions. Coexistence of 3-5 risk factors in subjects with abdominal obesity showed a significantly higher proportion than other clusters of risk factors (p<0.001). All of the six risk factors studied exhibited significant and independent associations with abdominal obesity in women, whereas in men, only smoking, low HDL-C levels, and hypertension were independent factors. In contradistinction to men, there was an over three-fold adjusted likelihood of diabetes to accompany abdominal obesity in women, with hypercholesterolemia significantly clustering with both. While abdominal obesity conferred an increased likelihood of coronary heart disease through mediation of five risk factors in women, it was found as a residual independent component in men. Conclusion: According to the NCEP ATP III criteria, abdominal obesity is three times more prevalent among Turkish women than in men. The female-specific combination of abdominal obesity, diabetes, and hypercholesterolemia may partly contribute to the comparatively high risk for cardiovascular disease in Turkish women. This study needs a re-evaluation of the role of abdominal obesity in Turkish men with a threshold of ≥96 cm, which was previously proposed by the authors.
Açıklama
Anahtar Kelimeler
Karın, Koroner Hastalık, Diyabetes Mellitus, Kadın, Hiperkolesterolemi, Hipertansiyon, Lipoprotein, HDL Kolesterol, Obezite, Risk Faktörü, Abdomen, Coronary Disease, Diabetes Mellitus, Female, Hypercholesterolemia, Hypertension, Lipoproteins, HDL Cholesterol, Obesity, Risk Factors
Kaynak
Türk Kardiyoloji Derneği Arşivi
Archives of the Turkish Society of Cardiology
Archives of the Turkish Society of Cardiology
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
33
Sayı
4
