In vitro screening of natural drug potentials for mass production

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dc.authorid0000-0002-6889-1562
dc.authorid0000-0002-5216-7588
dc.authorid0000-0002-8005-4425
dc.contributor.authorYaldız, Gülsüm
dc.contributor.authorÇalışkan, Ufuk Koca
dc.contributor.authorAka, Ceylan
dc.date.accessioned2021-06-23T19:49:02Z
dc.date.available2021-06-23T19:49:02Z
dc.date.issued2017
dc.departmentBAİBÜ, Ziraat Fakültesi, Tarla Bitkileri Bölümüen_US
dc.description.abstractMethanolic extracts of 16 plant species, used in herbal and traditional medicinal preparations, collected from the same geographic region (Golcuk-Seben/Bolu, Turkey) were evaluated for their relative total phenolic contents, total antioxidant activities and their mineral contents in both dried plant samples and methanolic extracts. These species included Hypericum perforatum L., Thymus sipyleus Boiss., Equisetum arvense L., Achillea millefolium L., Tanacetum parthenium L., Thymus leucostomus Hausskn. & Velen., Usnea longissima, Herniaria incana Boiss., Teucrium polium L., Stachys bithynica Boiss., Anthemis nobilis L., Sambucus ebulus L., Berberis vulgaris L., Malus communis Desf., Matricaria chamomilla L. and Scorzonera laciniata L. Spectrophotometric Folin-Ciocalteu and DPPH free radical scavenging activity methods were performed to detect the total phenolic contents and total antioxidant activities of the methanolic extracts, respectively. The results show that the fruits of Berberis vulgaris L., have the highest antioxidant activity and aerial parts of Tanacetum parthenium L. have the highest total phenolics (92.62%). Mineral contents were determined by inductively coupled -mass spectrometry (ICP-MS). All dried plant samples and methanolic extracts contained high amounts of Si, Cu, Fe and Ca. The highest levels of Si, Cu, Fe and Ca were found in Equisetum arvense L., Anthemis nobilis L., and Thymus sipyleus Boiss. dried plant samples, whereas Se was only detected in Usnea longissima. The highest levels of Si, Cu, Fe and Ca were found in the methanolic extracts of Usnea longissima, Anthemis nobilis L. and Thymus sipyleus Boiss. respectively.en_US
dc.identifier.doi10.15835/nbha45110397
dc.identifier.endpage300en_US
dc.identifier.issn0255-965X
dc.identifier.issn1842-4309
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85020271787en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage292en_US
dc.identifier.urihttps://doi.org/10.15835/nbha45110397
dc.identifier.urihttps://hdl.handle.net/20.500.12491/9325
dc.identifier.volume45en_US
dc.identifier.wosWOS:000403394200042en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorYaldız, Gülsüm
dc.language.isoenen_US
dc.publisherUniv Agr Sci & Veterinary Med Cluj-Napocaen_US
dc.relation.ispartofNotulae Botanicae Horti Agrobotanici Cluj-Napocaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntioxidanten_US
dc.subjectMedicinal Aromatic Plantsen_US
dc.subjectMineral Contentsen_US
dc.subjectPhenolicsen_US
dc.titleIn vitro screening of natural drug potentials for mass productionen_US
dc.typeArticleen_US

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