Evaluation of vitreous reflux and intraocular pressure changes in repeated intravitreal injections

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dc.authorid0000-0003-4468-3985
dc.authorid0000-0003-2544-3580
dc.contributor.authorUyar, Enes
dc.contributor.authorUlaş, Fatih
dc.date.accessioned2021-06-23T18:57:27Z
dc.date.available2021-06-23T18:57:27Z
dc.date.issued2020
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractPurpose: To evaluate effects of repeated intravitreal injections (IVIs) on vitreous reflux (VR) and intraocular pressure (IOP) changes in patients receiving intravitreal ranibizumab (IR) treatment. Materials and Methods: We retrospectively reviewed files of patients with wet type age-related macular degeneration or diabetic macular edema patients treated with IR and demographic information0, lens status, IOP values, amount of VR and data regarding intravitreal treatment were recorded in all patients. The study included 74 eyes of 74 patients who had complete data in a least 2 IVI sessions. Data obtained during the first IVI session (IVI1), second IVI session (IVI2) and data from third IVE session in 14 of 74 patients were analyzed. Results: In the study populations, there were 41 female (55.6%) and the mean age was 68.61 ± 9.81 (43-81) years. The mean number of IR injections was 4.89 ± 2.79 (1-10) and mean time was 7.1 ± 3.7 months (1-24 months) between IVI1 and IVI2. IOP values before and immediately after IVI were significantly higher in the IVI2 session, but there was no significant difference in IOP values on minute 30 after IVI (p: 0.032, <0.001, 0.518, respectively). The extent of IOP elevation after IVI was also significantly higher in IVI2 (p <0.001). The amount of VR was decreased in 44 patients (59.46%) whereas it was increased in 9 patients (12.16%) and no change was detected 21 patients (28.38%). There was no significant relationship between IOP changes after IVI and lens status, diagnosis, age and gender and (p> 0.05 for all data). Conclusion: It was found that repeated IVI applications decreased the amount of VR and therefore increased the frequency of short-term IOP after IVI.en_US
dc.identifier.doi10.37845/ret.vit.2020.29.40
dc.identifier.endpage231en_US
dc.identifier.issn1300-1256
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85095718432en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage227en_US
dc.identifier.trdizinid422265en_US
dc.identifier.urihttps://doi.org/10.37845/ret.vit.2020.29.40
dc.identifier.urihttps://hdl.handle.net/20.500.12491/5193
dc.identifier.volume29en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorUlaş, Fatih
dc.language.isoenen_US
dc.publisherGazi Eye Foundationen_US
dc.relation.ispartofRetina-Vitreusen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectIntraocular Pressureen_US
dc.subjectIntravitreal Injectionen_US
dc.subjectVitreous Refluxen_US
dc.titleEvaluation of vitreous reflux and intraocular pressure changes in repeated intravitreal injectionsen_US
dc.typeArticleen_US

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