Comparison of two different bronchodilators in the treatment of acute bronchiolitis

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dc.authorid0000-0003-4663-7157
dc.authorid0000-0002-8912-0361
dc.authorid0002-4030-1145-_
dc.contributor.authorÖzyürek, Hamit
dc.contributor.authorUyan, Ayten P.
dc.contributor.authorKeskin, Mahmut
dc.contributor.authorAfşar, Yılmaz
dc.contributor.authorKocabay, Kenan
dc.date.accessioned2021-06-23T18:54:51Z
dc.date.available2021-06-23T18:54:51Z
dc.date.issued2002
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBronchiolitis is an acute inflammatory respiratory illness of children less than two years of age. Therapies used in the treatment of bronchiolitis include adequate hydration, supplementary oxygen, bronchodilators, ribavirin, corticosteroids, immune globulin, interferon alfa and vitamin A. We enrolled 34 infants who were hospitalized for bronchiolitis to evaluate the efficacy of two different bronchodilators. Thirty-four infants under two years of age were randomized to receive either nebulized salbutamol (Group I) or nebulized ipratropium bromide (Group II). Clinical severity was scored on admission and 12-hour intervals after the start of nebulization. The symptom score evaluated five items: respiratory rate, presence of wheezing, presence of retraction, presence of nasal flaring, and general appearance. No difference was observed between the two groups in the clinical improvement on hospital admission and at the 12th, 24th, 36th and 48th hours during treatment. The mean duration of hospital stay was not significantly different between the two groups. When the groups were evaluated independently, there was a significant difference in scores before treatment and at the 48th hour of nebulization. We conclude that, ipratropium bromide and salbutamol are equally effective in the clinical recovery of bronchiolitis. Because of the side effects of salbutamol, ipratropium bromide may be primarily preferred as a bronchodilator.en_US
dc.identifier.endpage303en_US
dc.identifier.issn0010-0161
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-0036410333en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage298en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/4598
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-0036410333&partnerID=40&md5=5f6baf514e560927c4b22e63e8cdba17
dc.identifier.volume45en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorÖzyürek, Hamit
dc.institutionauthorUyan, Ayten P.
dc.institutionauthorKeskin, Mahmut
dc.institutionauthorAfşar, Yılmaz
dc.institutionauthorKocabay, Kenan
dc.language.isotren_US
dc.relation.ispartofÇocuk Sağlığı ve Hastalıkları Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBronchiolitisen_US
dc.subjectBronchodilatoren_US
dc.subjectIpratropium bromideen_US
dc.subjectTreatmenten_US
dc.titleComparison of two different bronchodilators in the treatment of acute bronchiolitisen_US
dc.title.alternativeAkut bronşiolit tedavisinde iki farklı bronkodilatörün etkinliğinin karşılaştırılmasıen_US
dc.typeArticleen_US

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