CRISPR/Cas9-mediated Immunity in Plants Against Pathogens

Basit Öğe Kaydı
dc.authoridKhan, Faheem Ahmed/0000-0002-3590-4320
dc.authoridGurel, Ekrem/0000-0001-6262-2866
dc.authoridSameeullah, Muhammad/0000-0001-6767-2539
dc.contributor.authorSameeullah, Muhammad
dc.contributor.authorKhan, Faheem Ahmed
dc.contributor.authorOzer, Goksel
dc.contributor.authorAslam, Noreen
dc.contributor.authorGurel, Ekrem
dc.contributor.authorWaheed, Mohammad Tahir
dc.contributor.authorKaradeniz, Turan
dc.date.accessioned2024-09-25T20:01:40Z
dc.date.available2024-09-25T20:01:40Z
dc.date.issued2018
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractGlobal crop production is highly threatened due to pathogen invasion. The huge quantity of pesticides application, although harmful to the environment and human health, is carried out to prevent the crop losses worldwide, every year. Therefore, understanding the molecular mechanisms of pathogenicity and plant resistance against pathogens is important. The resistance against pathogens is regulated by three important phytohormones, viz. salicylic acid (SA), jasmonic acid (JA) and ethylene (ET). Here we review the possible role of CRISPR technology to understand the plant pathogenicity by mutating genes responsible for pathogen invasion or up-regulating the phytohormones genes or resistant genes. Thus hormone biosynthesis genes, receptor and feeding genes of pathogens could be important targets for modifications using CRISPR/Cas9 following multiplexing tool box strategy in order to edit multiple genes simultaneously to produce super plants. Here we put forward our idea that the genes would be either mutated in case of plant receptor protein targets of pathogens or up-regulation of resistant genes or hormone biosynthesis genes will be better choice for resistance against pathogens.en_US
dc.identifier.doi10.21775/cimb.026.055
dc.identifier.endpage63en_US
dc.identifier.issn1467-3037
dc.identifier.issn1467-3045
dc.identifier.pmid28879856en_US
dc.identifier.startpage55en_US
dc.identifier.urihttps://doi.org/10.21775/cimb.026.055
dc.identifier.urihttps://hdl.handle.net/20.500.12491/14246
dc.identifier.volume26en_US
dc.identifier.wosWOS:000409374100005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMdpien_US
dc.relation.ispartofCurrent Issues in Molecular Biologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzYK_20240925en_US
dc.titleCRISPR/Cas9-mediated Immunity in Plants Against Pathogensen_US
dc.typeReview Articleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu