Anatomical and functional relationships between sensory nerves and mast cells

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dc.authorid0000-0001-5912-9392
dc.contributor.authorTöre, Fatma
dc.contributor.authorTuncel, Neşe
dc.date.accessioned2021-06-23T18:56:55Z
dc.date.available2021-06-23T18:56:55Z
dc.date.issued2011
dc.departmentBAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractMast cell and sensory nerve relationships fall into three categories: proximity, communication and a shared fate. Mast cells are found in all tissues of the human body, especially located closely to nerves. Mast-nerve membrane to membrane contact is a highly common configuration. This should be by design rather than by accident since such spatial distributions generally indicate a functional relationship. Mast cells associated to sensory nerves contain abundant neu-ropeptides and also a range of neuropeptide receptors enabling nerve to mast cell, mast cell to nerve and reciprocal communications which form the basis of neuroimmune interfacing. Wondering about the possible effects of this intimacy and communication potential on several physiological and pathophysiological events, specifically on diseases with low success rates of therapy and mysterious mechanisms, scientists have uncovered many aspects of mast-nerve interactions. In light of these studies, from a focal point between the nervous and immune systems, mast cells highlight the concept of collaboration as an indispensable building block of the neuroimmune system.en_US
dc.identifier.doi10.2174/187152311795325550
dc.identifier.endpage17en_US
dc.identifier.issn1871-5230
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-79952745388en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage10en_US
dc.identifier.urihttps://doi.org/10.2174/187152311795325550
dc.identifier.urihttps://hdl.handle.net/20.500.12491/5100
dc.identifier.volume10en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorTöre, Fatma
dc.language.isoenen_US
dc.publisherBentham Science Publishers B.V.en_US
dc.relation.ispartofAnti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCgrpen_US
dc.subjectMast Cellen_US
dc.subjectNeurogenic Inflammationen_US
dc.subjectNeuropeptideen_US
dc.subjectSensory Nerveen_US
dc.subjectSubstance Pen_US
dc.titleAnatomical and functional relationships between sensory nerves and mast cellsen_US
dc.typeArticleen_US

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