Could Mean Platelet Volume and Red Cell Distribution Width be related with the progression and severity of gestational hypertensive disorders?

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dc.authoridEkici, Mustafa Ayhan/0000-0002-0745-0907
dc.contributor.authorEkici, Mustafa Ayhan
dc.contributor.authorYis, Ozgur Mehmet
dc.date.accessioned2024-09-25T19:58:39Z
dc.date.available2024-09-25T19:58:39Z
dc.date.issued2022
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractObjective: To evaluate the correlation between thrombocyte indices, red cell distribution width and the progression of gestational hypertensive disorders Design: Retrospective and cross-sectional study Setting: Abant Izzet Baysal University Hospital and Bolu State Hospital, Bolu, Turkey Subjects: Five hundred and one pregnant women were included in this study, which included 115 severe-preeclampsia (PE), 155 mild-PE, 105 gestational hypertension (GHT) and 126 healthy pregnant women (control group). Intervention: 2 ml blood samples were taken by using 19-G needles. Hematological parameters values were studied using a blood count analyzer. Main outcome measure(s): Comparison of hematological parameters before and after diagnosis of GHT, mild-PE and severe-PE. Results: Mean platelet volume (MPV) was found significantly higher in the severe-PE group than GHT, mild-PE and control groups (P=0.005). MPV was higher in the severe-PE group concerning mild-PE and GHT groups (P=0.043, P=0.014 respectively), and it was unchanged between mild-PE, GHT and control groups. Platelet distribution width, red cell distribution width (RDW), plateletcrit, neutrophil/lymphocyte ratio and platelet/lymphocyte ratio were found unchanged among four groups. Platelet count (PC) was significantly lower in the severe-PE group than mild-PE, GHT and control groups (P=0.021). PC was not found to be significantly different among GHT, mild-PE and control groups. Hematological parameters before and after diagnosis of GHT, mild-PE and severe-PE were compared and RDW was significantly higher after progression of the disease (P=0.009, P=0.006, P=0.0002 respectively). Conclusions: Elevation in RDW levels is associated with a progression of GHT, mild PE and severe PE. MPV levels are found higher and PC levels are found lower in severe-PE. However, there was no significant change observed according to the severity of gestational hypertensive disorders.en_US
dc.identifier.endpage475en_US
dc.identifier.issn1607-8047
dc.identifier.issn0023-5776
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85149293988en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage469en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/13685
dc.identifier.volume54en_US
dc.identifier.wosWOS:001087350700003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherKuwait Medical Assocen_US
dc.relation.ispartofKuwait Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzYK_20240925en_US
dc.subjecthypertensionen_US
dc.subjectmean platelet volumeen_US
dc.subjectplatelet counten_US
dc.subjectplatelet distribution widthen_US
dc.subjectpreeclampsiaen_US
dc.titleCould Mean Platelet Volume and Red Cell Distribution Width be related with the progression and severity of gestational hypertensive disorders?en_US
dc.typeArticleen_US

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