Antiinflammatory and antinociceptive properties of luteolin diglucuronide and apigenin diglucuronide obtained from Perilla nankinensis

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dc.authorid0000-0002-5650-1280
dc.contributor.authorBüyükokuroğlu, Mehmet Emina
dc.contributor.authorBerashvili, Dalia
dc.contributor.authorGepdiremen, Ali Akçahan
dc.contributor.authorAltınkeser, Mustafa
dc.date.accessioned2021-06-23T18:54:06Z
dc.date.available2021-06-23T18:54:06Z
dc.date.issued2008
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractThis study aimed to examine possible antiinflammatory and antinociceptive effects of luteolin diglucuronide (LT), apigenin diglucuronide (AP) and semi-pure luteolin diglucuronide (S-LT) obtained from Perilla nankinensis in rats and mice. Antiinflammatory effects of LT, AP and S-LT were investigated with the carrageenaan-induced rat paw edema tests. It was found that pretreatment with LT, AP and S-LT obtained from Perilla nankinensis reduced inflammagen -induced paw edema in rats. Again, pretreatment with LT significantly diminished the nociceptive response in mice. LT and AP present in the leaves of Perilla nankinensis may partly account for the antiinflammatory and antinociceptive properties of Perilla nankinensis.en_US
dc.identifier.endpage1906en_US
dc.identifier.issn0970-7077
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-53949100898en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage1900en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/4223
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-53949100898&partnerID=40&md5=0dccbaf12170127ace5be1b274aea33a
dc.identifier.volume20en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorGepdiremen, Ali Akçahan
dc.language.isoenen_US
dc.relation.ispartofAsian Journal of Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnalgesicen_US
dc.subjectAntiinflammatoryen_US
dc.subjectMouseen_US
dc.subjectPerilla nankinensisen_US
dc.subjectRaten_US
dc.titleAntiinflammatory and antinociceptive properties of luteolin diglucuronide and apigenin diglucuronide obtained from Perilla nankinensisen_US
dc.typeArticleen_US

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