Antitumor activities of some Bellis perennis L. fractions

Basit Öğe Kaydı
dc.authorid0000-0001-5245-6294
dc.authorid0000-0001-9617-6673
dc.contributor.authorKarakaş, Pehlivan Fatma
dc.contributor.authorTürker, Uçar Arzu
dc.contributor.authorYalçın, F.
dc.contributor.authorÇalış, İhsan
dc.date.accessioned2021-06-23T19:26:54Z
dc.date.available2021-06-23T19:26:54Z
dc.date.issued2010
dc.departmentBAİBÜ, Fen Edebiyat Fakültesi, Biyoloji Bölümüen_US
dc.description7th Tannin Conference/58th International Congress and Annual Meeting of the Society-for-Medical-Plant-and-Natural-Product-Research -- AUG 29-SEP 02, 2010 -- Berlin, GERMANYen_US
dc.description.abstractBellis perennis L. has been used traditionally in the treatment of wounds, catarrh, rheumatism, arthritis, liver, kidney and respiratory tract disorders [1–3]. In this study, antitumor activities of nine different fractions (F.1, 3–4, 5, 6–7, 8, 9, 10–11, 12, 13–15) of B. perennis at different concentrations (10000, 1000 and 100mg/l) were evaluated using the Agrobacterium tumefaciens Potato Disc Tumor Bioassay modified by McLaughlin's group [4]. The inhibition of A. tumefaciens-induced tumors (or crown gall) in potato disc tissue is an assay based on antimitotic activity and can detect a broad range of known and novel antitumor efffects [5,6]. The validity of this bioassay is predicted on the observation that certain tumorigenic mechanisms are similar in plants and animals. It has been shown that the inhibition of crown gall tumor initiation on potato discs and subsequent growth showed good correlation with compounds and extracts active in the 3PS (P388) (in vivo murine leukemia) leukemic mouse assay [6,7]. All tested fractions at all concentrations showed tumor inhibitions. However, 100% tumor inhibition was observed with F.10–11at 10.000mg/l similar to Camptothecin (positive control).en_US
dc.description.sponsorshipSoc Med Plant Nat Prod Resen_US
dc.identifier.endpage1261en_US
dc.identifier.issn0032-0943
dc.identifier.issue12en_US
dc.identifier.startpage1261en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6684
dc.identifier.urihttps://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0030-1264574
dc.identifier.volume76en_US
dc.identifier.wosWOS:000282066500395en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.institutionauthorKarakaş, Pehlivan Fatma
dc.institutionauthorTürker, Uçar Arzu
dc.language.isoenen_US
dc.publisherGeorg Thieme Verlag Kgen_US
dc.relation.ispartofPlanta Medicaen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBellis Perennisen_US
dc.titleAntitumor activities of some Bellis perennis L. fractionsen_US
dc.typeConference Objecten_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Biyoloji Bölümü Koleksiyonu