Comparison of imaging studies and diagnostic tests for the diagnosis and follow-up of recurrent urinary tract infection in children

Basit Öğe Kaydı
dc.authorid0000-0003-0120-9976
dc.authorid0002-4030-1145-
dc.contributor.authorŞimşek, Enver
dc.contributor.authorKoloğlu, Nuri
dc.contributor.authorYugunt, İbrahim
dc.contributor.authorKocabay, Kenan
dc.date.accessioned2021-06-23T18:54:36Z
dc.date.available2021-06-23T18:54:36Z
dc.date.issued2004
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective: To compare the imaging studies and diagnostic tests for the diagnosis and follow-up of urinary tract infection (UTI) in children. Methods: Ninety-two children with recurrent urinary tract infection were studied. Urinalysis, dipstick examination of urine for leukocyte-esterase (LE) and nitrite reaction, urine culture, sedimentation rate, C-reactive protein, renal ultrasonography, and voiding cystourethrography (VCUG) were performed. The renal cortical 99mTC dimercaptosuccinic acid (DMSA) scanning was performed during the acute phase of infection for the localization of UTI in some patients and after six months of the treatment in all patients. VCUG was performed six months later again in children who had vesicoureteral reflux (VUR). Intravenous pyelography (IVP) was used for selected cases to screen for urinary obstruction or malformations. Results: All children were followed-up until 39 months. Of the 92 patients, the prevalence of pyuria and bacteriuria were found in 74 (80.4%) and 78 (85%), respectively; hematuria in 62 (67%); and positive LE and nitrite on dipstick in 48 (52%) and 30 (33%) children, respectively. Sedimentation rate was higher than 20 mm/hour in 76 (83%) children. Positive C-reactive protein (CRP) level (> 10 mg/dl) was found in 68 (74%) children. Of the 92 children, 82 (89%) had positive culture result: 64 (78%) females and 18 (22%) males. Renal ultrasonography (US) was abnormal in 28 (30%) children. Renal scarring was revealed by DMSA scanning in 56 (61%) children. DMSA was abnormal in 34 (37%) children who had normal renal ultrasonography, and in 22 (24%) children who had normal VCUG. Ultrasound was abnormal in 2 (2%) children who had normal DMSA. VCUG showed grade I reflux in one (1%) patient who had normal DMSA. IVP revealed VUR in 4 (4%) children who had normal US. DMSA was abnormal in all patients who had abnormal IVP findings. Conclusion: Using the combination of urinalysis, dipstick examination for leukocyte esterase, sedimentation rate, and CRP as screening tests in symptomatic patients, prevents overdiagnosis of UTI and unnecessary treatment. Renal ultrasonography, VCUG, and renal cortical DMSA scanning should be the minimum imaging studies for the evaluation of recurrent UTI in children. IVP is recommended only for selected cases when anatomic detail is required.en_US
dc.identifier.endpage113en_US
dc.identifier.issn0885-6265
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-2942530848en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage109en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/4502
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-2942530848&partnerID=40&md5=936fa863de39e4d760f53b231c90fdac
dc.identifier.volume19en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorŞimşek, Enver
dc.institutionauthorKoloğlu, Nuri
dc.institutionauthorYugunt, İbrahim
dc.institutionauthorKocabay, Kenan
dc.language.isoenen_US
dc.relation.ispartofInternational Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectUrinary Tract Infection (UTI)en_US
dc.subjectComparison
dc.titleComparison of imaging studies and diagnostic tests for the diagnosis and follow-up of recurrent urinary tract infection in childrenen_US
dc.typeArticleen_US

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