Effectiveness of rapid antigen test with throat gargle in detecting group A beta-hemolytic streptococci

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dc.authorscopusid20136555600
dc.authorscopusid23060531400
dc.authorscopusid56651969500
dc.authorscopusid6602989167
dc.authorscopusid13611182300
dc.contributor.authorYilmaz, Fahrettin
dc.contributor.authorKarabay, O?uz
dc.contributor.authorInce, Nevin Koç
dc.contributor.authorEkerbiçer, Hasan
dc.contributor.authorKoço?lu, Esra
dc.date.accessioned2024-09-25T19:44:00Z
dc.date.available2024-09-25T19:44:00Z
dc.date.issued2008
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractOBJECTIVES: The most important disadvantage of rapid antigen tests (RAT) is low sensitivity for the diagnosis of group A beta-hemolytic streptococci (BHS). We determined the sensitivity, specificity, positive and negative predictive values of RAT in gargling samples. PATIENTS AND METHODS: The study included 106 patients (53 females, 53 males, mean age 22+/-12 years; range 16-65 years) with an initial diagnosis of tonsillopharyngitis. Swab samples were taken from the posterior pharyngeal wall and tonsil surface with a sterile cotton swab. Then, gargle samples were obtained by gargling for 10 seconds with sterile 0.9% NaCl to be examined by the RAT for group A BHS. Throat cultures were processed using standard microbiologic techniques. RESULTS: Throat cultures were positive in 12 patients (11.3%) and negative in 94 patients (88.6%). Rapid antigen test yielded five positive (4.7%) and 101 negative (95.2%) results. The sensitivity and specificity rates of RAT with throat gargling were 41.7% and 100%, with positive and negative predictive values of 100% and 93.1%, respectively. CONCLUSION: Despite satisfactory specificity, positive and negative predictive rates of RAT with throat gargling, its low sensitivity limits its use for the diagnosis of group A BHS.en_US
dc.identifier.endpage283en_US
dc.identifier.issn1300-7475
dc.identifier.issue5en_US
dc.identifier.pmid19155672en_US
dc.identifier.scopus2-s2.0-77955900081en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage280en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/12591
dc.identifier.volume18en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isotren_US
dc.relation.ispartofKulak burun bo?az ihtisas dergisi : KBB = Journal of ear, nose, and throaten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzYK_20240925en_US
dc.subjectAdolescenten_US
dc.subjectAdulten_US
dc.subjectAgeden_US
dc.subjectAntigens, Bacterialen_US
dc.subjectFemaleen_US
dc.subjectHumansen_US
dc.subjectMaleen_US
dc.subjectMiddle Ageden_US
dc.subjectPalatine Tonsilen_US
dc.subjectPharynxen_US
dc.subjectSensitivity and Specificityen_US
dc.subjectStreptococcal Infectionsen_US
dc.subjectStreptococcus pyogenesen_US
dc.subjectTonsillitisen_US
dc.subjectYoung Adulten_US
dc.subjectbacterial antigenen_US
dc.subjectadolescenten_US
dc.subjectadulten_US
dc.subjectageden_US
dc.subjectarticleen_US
dc.subjectfemaleen_US
dc.subjecthumanen_US
dc.subjectimmunologyen_US
dc.subjectisolation and purificationen_US
dc.subjectmaleen_US
dc.subjectmicrobiologyen_US
dc.subjectmiddle ageden_US
dc.subjectpalatine tonsilen_US
dc.subjectpharynxen_US
dc.subjectsensitivity and specificityen_US
dc.subjectStreptococcus infectionen_US
dc.subjectStreptococcus pyogenesen_US
dc.subjecttonsillitisen_US
dc.titleEffectiveness of rapid antigen test with throat gargle in detecting group A beta-hemolytic streptococcien_US
dc.title.alternativeBo?az gargarasi ile yapilan hizli antijen testinin grup A beta-hemolitik streptokoklari saptamadaki etkinli?i.]en_US
dc.typeArticleen_US

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