Evaluation of the efficacy of rectalmisoprostol versus intravenous oxytocin for the prevention of postpartumhemorrhage

dc.contributor.authorGul, Ozlem Kemik
dc.contributor.authorSomunkiran, Asli
dc.contributor.authorOzdemir, Ismail
dc.contributor.authorYucel, Oguz
dc.contributor.authorDemirci, Fuat
dc.date.accessioned2024-09-25T19:58:53Z
dc.date.available2024-09-25T19:58:53Z
dc.date.issued2006
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractObjective: To compare the effectiveness of rectally administered prostaglandine E1 anolog misoprostol and parenterally oxytocin for the prevention of postpartum hemorrhage. Design: Prospective randomized trial Setting: University hospital Patients: 240 full term pregnant women who were in active labor. Interventions: 80 patients in group 1 received 200 mu g misoprostol rectally, 80 patients in Group 2 received 400 mu g rectally misoprostol, and the third group received a solution of 1000 ml 5% DRL + 10 IU oxytocin, immediately after the delivery of the fetus. Main outcome measures: Postpartum blood loss and potential side effects of misoprostol were evaluated. Results: No statistically significant difference was found among the three groups regarding the average blood loss (F=1.50, p=0.22). Average duration of the third stage of labor was similar in all groups (F=1.13, p=0.32). Hematocrit values were similar in the groups both before (F=3.28, p=0.52) and after the delivery and (F=1.84, p=0.16). Conclusions: No differences were found between rectallymisoprostol and oxytocin treatment for the prevention of postpartum hemorrhage. Nevertheless, misoprostol can be preferred in the prevention of postpartum hemorrhage because it does not require special storage conditions, can be used safely in hypertensive patients, can be stored for many years, it is resistant to heat and its side effects such as nausea and vomiting are low when used rectally.en_US
dc.identifier.endpage166en_US
dc.identifier.issn2149-9322
dc.identifier.issn2149-9330
dc.identifier.issue3en_US
dc.identifier.startpage162en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/13813
dc.identifier.volume3en_US
dc.identifier.wosWOS:000409142900004en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofTurkish Journal of Obstetrics And Gynecologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzYK_20240925en_US
dc.subjectmisoprostolen_US
dc.subjectoxytocinen_US
dc.subjectpostpartum hemorrhageen_US
dc.titleEvaluation of the efficacy of rectalmisoprostol versus intravenous oxytocin for the prevention of postpartumhemorrhageen_US
dc.typeArticleen_US

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