Conformational control on remote stereochemistry in the intramolecular pauson-khand reactions of enynes tethered to homoallyl and homopropargyl alcohols

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Küçük Resim

Tarih

2006

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Pergamon-Elsevier Science Ltd

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

An intramolecular Pauson-Khand reaction of enynes derived from homoallyl and homopropargyl alcohols is described. 2-Furyl substituted homoallyl and homopropargyl alcohols are easily and efficiently resolved through enzymatic resolution in a high ee (93-99%) with a known stereochemistry. Each enantiomerically enriched enyne affords the conformationally most stable diastereomeric cyclopenta[c]pyran ring system.

Açıklama

Anahtar Kelimeler

Conformational Control, Stereochemistry, Homopropargyl, Intramolecular

Kaynak

Tetrahedron-Asymmetry

WoS Q Değeri

Q2

Scopus Q Değeri

N/A

Cilt

17

Sayı

21

Künye