A rapid and efficient protocol for the synthesis of novel nitrothiazolo [3,2-c]pyrimidines via microwave-mediated Mannich cyclisation

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dc.authorid0000-0002-0873-694Xen_US
dc.authorid0000-0002-8658-3897en_US
dc.authorid0000-0003-2933-5296
dc.contributor.authorYıldırım, Muhammet
dc.contributor.authorÇelikel, Derya
dc.contributor.authorDürüst, Yaşar
dc.contributor.authorKnight, David W.
dc.contributor.authorKariuki, Benson M.
dc.date.accessioned2021-06-23T19:36:11Z
dc.date.available2021-06-23T19:36:11Z
dc.date.issued2014
dc.departmentBAİBÜ, Fen Edebiyat Fakültesi, Kimya Bölümüen_US
dc.description.abstractSeveral 6-substituted-8-nitrothiazolo[3,2-c]pyrimidine derivatives have been obtained very efficiently by a multicomponent cyclisation of 2-(nitromethylene)thiazolidine, formaldehyde and various aliphatic or aromatic amines in water, using both microwave irradiation and conventional heating. Reaction yields were considerably higher and the reaction times very much reduced using microwave heating when compared to conventional heating, resulting in the definition of a rapid and efficient synthetic protocol. (C) 2014 Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.tet.2014.02.003
dc.identifier.endpage2128en_US
dc.identifier.issn0040-4020
dc.identifier.issue12en_US
dc.identifier.scopus2-s2.0-84896735399en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2122en_US
dc.identifier.urihttps://doi.org/10.1016/j.tet.2014.02.003
dc.identifier.urihttps://hdl.handle.net/20.500.12491/7946
dc.identifier.volume70en_US
dc.identifier.wosWOS:000332803900007en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorYıldırım, Muhammet
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofTetrahedronen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNitroenamineen_US
dc.subjectOne-pot Reactionen_US
dc.subjectMulticomponenten_US
dc.subjectMannichen_US
dc.subjectMicrowave Heatingen_US
dc.titleA rapid and efficient protocol for the synthesis of novel nitrothiazolo [3,2-c]pyrimidines via microwave-mediated Mannich cyclisationen_US
dc.typeArticleen_US

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