The prognostic value of mean platelet volume in decompensated heart failure

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dc.authorscopusid8587924200
dc.authorscopusid8615642100
dc.authorscopusid25121970100
dc.authorscopusid8650271300
dc.authorscopusid36105714600
dc.authorscopusid35338946100
dc.authorscopusid36164792500
dc.contributor.authorKandis, Hayati
dc.contributor.authorOzhan, Hakan
dc.contributor.authorOrdu, Serkan
dc.contributor.authorErden, Ismail
dc.contributor.authorCaglar, Onur
dc.contributor.authorBasar, Cengiz
dc.contributor.authorYalcin, Subhan
dc.date.accessioned2024-09-25T19:44:15Z
dc.date.available2024-09-25T19:44:15Z
dc.date.issued2011
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractBackground: Congestive heart failure (CHF) is a major public health problem that is related to substantial morbidity, impaired quality of life and diminished survival. Mean platelet volume (MPV) is an indicator of platelet activation. Aim: To investigate whether there is a difference of MPV in patients with decompensated and stable heart failure (SHF), and test the prognostic value of MPV in decompensated heart failure (DHF). Methods: 136 consecutive patients with DHF were enrolled. 71 with SHF were also enrolled for comparison. Patients were followed up for a mean of 18±12 months. The primary endpoint was death from any cause. Clinical characteristics of patients with DHF who died during follow-up were compared with the those of the survivors. Results: MPV was significantly higher in DHF group than in the SHF group. 71 patients died during the follow-up period (18±12 months). Comparison with survivors revealed that mortality was associated with age, systolic blood pressure, pulmonary artery pressure, serum creatinine, urea and MPV. MPV was determined as an independent risk factor for mortality (OR 1.553, 95% CI 1.024 to 2.354, p=0.038). Receiver operating characteristic analysis showed that MPV level on admission was a predictor of mortality (area under the curve (AUC) for in-hospital mortality was 0.716 (95% CI 0.632 to 0.789, p=0.003) and AUC for 6-month mortality was 0.815 (95% CI 0.74 to 0.877, p<0.001), respectively). Conclusion: MPV is increased in patients with DHF. Also, MPV on admission is an independent predictor of in-hospital mortality and 6-month mortality.en_US
dc.identifier.doi10.1136/emj.2009.088401
dc.identifier.endpage578en_US
dc.identifier.issn1472-0213
dc.identifier.issue7en_US
dc.identifier.pmid20660896en_US
dc.identifier.scopus2-s2.0-79959575003en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage575en_US
dc.identifier.urihttps://doi.org/10.1136/emj.2009.088401
dc.identifier.urihttps://hdl.handle.net/20.500.12491/12740
dc.identifier.volume28en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofEmergency Medicine Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzYK_20240925en_US
dc.subjectAgeden_US
dc.subjectBiological Markersen_US
dc.subjectBlood Plateletsen_US
dc.subjectCell Sizeen_US
dc.subjectFemaleen_US
dc.subjectFollow-Up Studiesen_US
dc.subjectHeart Failureen_US
dc.subjectHospital Mortalityen_US
dc.subjectHumansen_US
dc.subjectLogistic Modelsen_US
dc.subjectMaleen_US
dc.subjectMiddle Ageden_US
dc.subjectPrognosisen_US
dc.subjectcreatinineen_US
dc.subjecthemoglobinen_US
dc.subjectsodiumen_US
dc.subjectureaen_US
dc.subjectage distributionen_US
dc.subjectageden_US
dc.subjectarticleen_US
dc.subjectcreatinine blood levelen_US
dc.subjectfemaleen_US
dc.subjectfollow upen_US
dc.subjectheart failureen_US
dc.subjecthumanen_US
dc.subjectlung artery pressureen_US
dc.subjectmajor clinical studyen_US
dc.subjectmaleen_US
dc.subjectmean platelet volumeen_US
dc.subjectmortalityen_US
dc.subjectpriority journalen_US
dc.subjectprognosisen_US
dc.subjectrisk factoren_US
dc.subjectsurvivoren_US
dc.subjectsystolic blood pressureen_US
dc.subjectthrombocyte volumeen_US
dc.titleThe prognostic value of mean platelet volume in decompensated heart failureen_US
dc.typeArticleen_US

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