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Öğe Annelerin çocuklarındaki ateşle ilgili bilgi tutum ve davranışları(2005) Baysoy, Gökhan; Aydoğmuş, Tuğba; Akın, Demet; Uyan, Ayten PamukçuAmaç: Annelerin ateş konusundaki bilgi düzeylerinin ve bu bilginin kaynağının saptanması, ateş karşısındaki tutum, davranış ve korkularının belirlenmesi amaçlanmıştır. Ayrıca, ateş konusunda daha önceden bilgilendirilmiş ve bilgilendirilmemiş anneler, ateş konusundaki bilgi düzeyleri, yaklaşımları, derece ve ateş düşürücü kullanımları açısından karşılaştırılmıştır. Gereç ve Yöntem: Çalışmaya Abant İzzet Baysal Üniversitesi ve Bolu'daki sağlık merkezlerine Ocak-Temmuz 2004 tarihleri arasında başvuran 285 anne dahil edilmiştir. Annelere, ailenin demografik yapısı, ateşin tanımı, ateşi ölçme yöntemleri ve bu yöntemlerin hangilerinin kullanıldığı, ateş düşürücü kullanımı, annenin ateşin yükselmesi durumunda yaptıklarını içeren bir anket uygulanmıştır. Bulgular: Çalışmaya katılan annelerin üçte ikisi ateş konusunda bilgi almış olup bu bilginin %80'i sağlık çalışanı tarafından verilmiştir. Bu çalışmaya katılan annelerin %72'si derece kullanarak ateş ölçerken, bu oranın ateş konusunda bilgi alan annelerde almayanlara oranla daha fazla olduğu görülmüştür. Evde ateş düşürmede en sık kullanılan ilacın parasetamol olduğu saptanmıştır. Ateş düşürücülerin genellikle önerilenden daha sık aralıklarla kullanıldığı da belirlenmiştir. Çıkarımlar: Ateş konusunda bilgilendirilmiş olmanın daha çok derece kullanımı ve etkili ateş düşürücü yöntem bilgisiyle ilişkili olduğu gözlenmiştir. Ateş konusunda bilgilendirilmiş olmanın ateş korkusunu azaltmadığı saptanmıştır. Ateş konusunda ailelere verilecek bilgilerin, ailelerdeki ateş korkusunu azaltmaya yönelik bir içeriği olmasına da dikkat edilmelidir.Öğe Annelerin, çocuklarındaki ateşle ilgili bilgi, tutum ve davranışları(2005) Baysoy, Gökhan; Aydoğmuş, Tuğba; Akin, Demet; Uyan, Pamukçu AytenAmaç: Annelerin ateş konusundaki bilgi düzeylerinin ve bu bilginin kaynağının saptanması, ateş karşısındaki tutum, davranış ve korkularının belirlenmesi amaçlanmıştır. Ayrıca, ateş konusunda daha önceden bilgilendirilmiş ve bilgilendirilmemiş anneler, ateş konusundaki bilgi düzeyleri, yaklaşımları, derece ve ateş düşürücü kullanımları açısından karşılaştırılmıştır. Gereç ve Yöntem: Çalışmaya Abant İzzet Baysal Üniversitesi ve Bolu'daki sağlık merkezlerine Ocak-Temmuz 2004 tarihleri arasında başvuran 285 anne dahil edilmiştir. Annelere, ailenin demografik yapısı, ateşin tanımı, ateşi ölçme yöntemleri ve bu yöntemlerin hangilerinin kullanıldığı, ateş düşürücü kullanımı, annenin ateşin yükselmesi durumunda yaptıklarını içeren bir anket uygulanmıştır. Bulgular: Çalışmaya katılan annelerin üçte ikisi ateş konusunda bilgi almış olup bu bilginin %80'i sağlık çalışanı tarafından verilmiştir. Bu çalışmaya katılan annelerin %72'si derece kullanarak ateş ölçerken, bu oranın ateş konusunda bilgi alan annelerde almayanlara oranla daha fazla olduğu görülmüştür. Evde ateş düşürmede en sık kullanılan ilacın parasetamol olduğu saptanmıştır. Ateş düşürücülerin genellikle önerilenden daha sık aralıklarla kullanıldığı da belirlenmiştir. Çıkarımlar: Ateş konusunda bilgilendirilmiş olmanın daha çok derece kullanımı ve etkili ateş düşürücü yöntem bilgisiyle ilişkili olduğu gözlenmiştir. Ateş konusunda bilgilendirilmiş olmanın ateş korkusunu azaltmadığı saptanmıştır. Ateş konusunda ailelere verilecek bilgilerin, ailelerdeki ateş korkusunu azaltmaya yönelik bir içeriği olmasına da dikkat edilmelidir.Öğe Ascites and pleural effusion: Rare complications of hepatitis A infection in children(2009) Yolcu, Canan Turgut; Uyan, Ayten Pamukçu; Baysoy, GökhanPleural effusion is a rare complication of atypical hepatitis A virus infection. It was proposed that immune complexes or local inflammation within the liver might be the cause of pleural effusion. In this case report, an 8 year-old girl with hepatitis A virus infection and unilateral pleural effusion was presented and the pathogenesis of this relation was discussed.Öğe Asit ve plevral efüzyon: Çocuklarda hepatit A infeksiyonunun nadir komplikasyonları(2009) Yolcu, Canan Turgut; Uyan, Ayten Pamukçu; Baysoy, GökhanPlevral efüzyon, atipik hepatit A virus (HAV) infeksiyonunun nadir bir komplikasyonudur. Plevral efüzyondan infeksiyon sırasında ortaya çıkan immün komplekslerin ya da karaciğerdeki lokal inflamasyonun sorumlu olabileceği ileri sürülmüştür. Bu yazıda, HAV infeksiyonu sırasında tek taraflı plevral efüzyon gelişen 8 yaşında bir kız hasta sunularak bu durumun patogenezi tartışılmıştır.Öğe Aşı sonrası gelişen geçici fontanel bombeleşmesi(2008) Baysoy, Gökhan; Uyan, Ayten PamukçuGeçici fontanel bombeleşmesi bebeklik döneminde nadir görülmektedir. Etiyolojide altıncı hastalık, viral infeksiyonlar, aşılar ve yüksek doz A vitamini uygulaması yer almaktadır. Bu yazıda DBT-IPV-Hib kombine aşısından sonra geçici fontanel bombeleşmesi saptanan 4.5 aylık bir bebek sunularak nadir görülen bu duruma ve ayırıcı tanısına dikkat çekilmek istenmiştir.Öğe Çocukluk çağında tüberkülozun farklı klinik formları: Üç olgu(2008) Uyan, Ayten Pamukçu; Baysoy, GökhanÇocukluk çağı tüberkulozu (TB) morbidite ve mortalitenin önemli bir nedenidir ve tahminlere göre tüm vakaların %95’i gelişmekte olan ülkelerde bulunur. Gelişmiş ülkelerde çocukluk çağı tüberkülozunun tüm vakalara katkısı %3-6 iken, gelişmekte olan ülkelerde bu oran daha büyüktür (%15-20). TB’un tanısı çocuklarda oldukça güçtür, nadiren doğrulanır ve çoğunlukla klinik bulgular, semptomlar, erişkin ile temas hikayesi ve özel araştırmalara dayandırılır. Çocuklarda TB, az sayıda basil içeren yapısından dolayı, genellikle yayma negatiftir. Mycobacterium Tuberculosis (MT) kültürü ile bakteriyolojik doğrulama tanıda altın standarttır, ancak nadiren %30-40’ı geçer. Bu yazıda, TB tanısı alan ve tedavi edilen üç farklı TB olgusunu sunmak istedik.Öğe Concurrent septic arthritis and urinary tract infection in a patient with nephrocalcinosis and vesicoureteral reflux(Turkish J Pediatrics, 2006) Baysoy, Gökhan; Gürel, Safiye; Çakıcı, Hüsamettin; Uyan, Ayten P.An eight-month-old boy who presented with a 15-day history of vomiting was revealed to be suffering from urinary tract infection and nephrocalcinosis caused by vitamin D intoxication. During the treatment of vitamin D intoxication (alendronate, 5 mg/day), he developed urinary tract infection and septic arthritis of the left hip joint. Escherchia coli was isolated from his blood, urine, and joint fluid culture. He was operated, joint drainage was performed and appropriate intravenous antibiotic treatment was given for four weeks. After discharge, a voiding cystoureterogram revealed grade 4 vesicoureteral reflux in the right ureter. Combination of complex urinary anomalies associated with stagnation of urine flow and altered urinary dynamics, and metabolic urinary anomalies, such as hypercalciuria/nephrocalcinosis, may facilitate the occurrence of rare systemic complications of urinary tract infection.Öğe Coxiella Burnetii seroprevalence in the rural part of Bolu, Turkey(2009) Karabay, Oğuz; Koçoğlu, Esra; Baysoy, Gökhan; Konyalıoğlu, SelamiAim: This study was performed to determine the seroprevalence of Coxiella burnetii in the rural part of Bolu, a city located in the western part of the Black Sea region of Turkey. Materials and Methods: The study population was chosen by cluster sampling to represent the rural population of the city. Serum samples were collected from the 9 rural districts of Bolu. Blood samples were taken to the laboratory while stored at 4 °C in ice-cooled boxes. The sera were then stored at −20 °C until testing. The presence of IgG antibodies against C. burnetii phase-II antigens in the sera was determined using IFA. Results: The study included 293 cases and C. burnetii phase-II IgG was positive in 61 of the subjects (20.8%). The seroprevalence of C. burnetii was 23.8% (59/248) among the participants above 18 years of age and 4.4% (2/45) among those younger than 18 years of age (P < 0.01). There was a significant relationship between C. burnetii seropositivity and direct contact with the birth products of farm animals (P < 0.001); however, there was not a significant difference between genders. Conclusions: Although the seroprevalence rate was high, Q fever was underreported and unrecognized in rural Bolu. We conclude that Q fever must be considered in patients with a suitable clinical course in this region.Öğe Early diagnosis of iliopsoas pyomyositis by computed tomography and muscle biopsy in an epileptic child(Springer, 2007) Baysoy, Gökhan; Gürel, Kamil; Uyan, Ayten P.Pyomyositis is an acute pyogenic infection of the skeletal muscle due to transient bacteremia in the setting of preexisting or concurrent muscular injury [1]. We present a case of iliopsoas pyomyositis diagnosed at the early suppurative phase by computed tomography (CT) and fine needle aspiration/biopsy (FNAB)Öğe Epidemiological study of constipation and other gastrointestinal symptoms in 8000 children (Acta Paediatr 2006; 95 : 573-580)(Blackwell Publishing, 2007) Baysoy, GökhanSir,I read the article by Ludvigsson, JF for the ABIS studygroup with interest (1). This large population-based co-hort study demonstrates an interesting relationship betweenanorexia and paracetamol use between 1 and 2.5 years.Anorexia might be a result of abdominal pain; however, au-thors have clearly suggested that paracetamol use was notlinked to abdominal pain. Anorexia as well as abdominalpain is more common in constipated children (2). RomaEetal.demonstrated that anorexia was 27.5% in consti-pated children and 5.2% in control subjects. We also in-vestigated the prevalence and associated factors in consti-pation in Bolu in 3453 primary school children (age 6–14years) (a city located in the western Black Sea region ofTurkey) and found that 12.7% of 820 constipated childrenhad poor appetite (whereas remaining had good or moder-ate appetite according to mothers) compared to 7.3% in non-constipated children according to the mother’s self report(p<0.01, OR=1.895% CI 1.4–2.3) (3). So it might be in-teresting to examine the correlation of anorexia to paraceta-mol use while controlling for the constipation in the presentstudy.Öğe IBS and depression in young adults in Turkey : results of a questionnaire survey(Springer Tokyo, 2007) Baysoy, Gökhan; Baysoy, Nüket Güler; Kesicioğlu, Aynur; Akın, Demet; Dündar, Tuğba; Uyan, Ayten P.We read the article by Shiotani et al.1 with great enthusiasm. These authors stated that epidemiological studies of irritable bowel syndrome (IBS) among young adults are few, especially in Asian countries. We have just finished the first part of a similar study in Abant Izzet Baysal University in Turkey.Öğe Linkage analysis and a novel COL4A5 mutation in a large Turkish family with Alport syndrome(Medecine Et Hygiene, 2011) Tuğ, Esra; Perçin, Ferde Emriye; Pala, Elif; Baysoy, GökhanLinkage analysis and a novel COL4A5 mutation in a large Turkish family with Alport syndrome: Background: Alport syndrome (AS) is a renal disease that is characterized by proteinuria and progressive renal failure, and often accompanied by sensorineural hearing loss and ocular changes. Mutations in the genes encoding for three members of the type IV collagen protein family have been found to be the cause of the disease. We describe a large Turkish family with X-linked AS. We performed linkage analysis in this family and sequencing to identify the mutation in the proband whose disease was confirmed by renal biopsy. Methods: After genomic DNAs extracted, linkage to the COL4A5 locus was examined using the 2B6 and 2B20, DXS1106, DXS1105 and COL4A5 markers. In addition, COL4A5 gene sequence analysis was performed in the proband Results: Genetic linkage analysis demonstrated co-segregation of the disease. Haplotype analysis showed that the same haplotype was carried by all affected males and obligatory carrier females. Mutation analysis of the proband has revealed a novel nonsense mutation (c.1135C>T; Gln379X) in exon 19 of the COL4A5 gene which may lead to a more severe phenotype in affected family members carrying this mutation. According to GenBank data base, this mutation has not been reported previously. Conclusion: Genetic testing identified a previously undescribed COL4A5 mutation as the cause of the disease.Öğe Nasal carriage of Staphylococcus aureus in children with allergic rhinitis and the effect of intranasal fluticasone propionate treatment on carriage status(Elsevier Ireland Ltd, 2007) Baysoy, Gökhan; Arslan, Sezai; Karabay, Oğuz; Uyan, Ayten P.Objective: The aim of this study is to determine the rate of nasal carriage of Staphylococcus aureus (NCSA) in children with allergic rhinitis (AR) and to determine the effect of intranasal fluticasone propionate spray on the NCSA. Patients and methods: Nasal swabs were taken from the children admitted to general pediatrics and pediatric pulmonology clinics. Patients were divided into two groups according to the presence or absence of AR. Diagnosis of AR was based on the patient's symptoms. Nasal swabs were taken from AR patients before and after the treatment with intranasal fluticasone propionate, and from the control group at the beginning and after 2 months. Results: Whole NCSA rate was 17.9%; it was 21.4% for AR patients and 15.9% for control group, respectively (p > 0.05). Treatment with intranasal fluticasone propionate spray did not influence NCSA in AR patients. Conclusion: It seemed that NCSA was not increased in children with AR and treatment with intranasal fluticasone propionate spray did not change NCSA in AR patients. It is obvious that better understanding of the factors affecting the acquisition and loss of NCSA might increase our knowledge about the relationship between NCSA, allergic airway diseases and their treatments. (C) 2006 Elsevier Ireland Ltd. All rights reserved.Öğe Prevalence of irritable bowel syndrome in adolescents in Turkey: Effects of gender, lifestyle and psychological factors(Turkish National Pediatric Society, 2014) Baysoy, Gökhan; Baysoy, Nüket Güler; Kesicioğlu, Aynur; Akın, Demet; Dündar, Tuğba; Uyan, Ayten PamukçuScarce data exist concerning the prevalence of irritable bowel syndrome in adolescence. Changes in lifestyle, presence of stressors and psychological vulnerability during this stage of life place adolescents in the risk group for irritable bowel syndrome. The aim of this study is to determine the prevalence of irritable bowel syndrome in adolescents who are about to begin their university studies and to identify lifestyle and psychological factors related to irritable bowel syndrome. All students newly enrolled at Abant Izzet Baysal University during the 2005-2006 academic year were recruited. Questionnaires including the Rome II questionnaire, the Beck Depression Inventory and the State-Trait Anxiety Inventory were sent to the addresses of the eligible students before matriculation to the university. A total of 2217 students completed the questionnaires, of which 2038 (91.9%) were regarded as valid. Irritable bowel syndrome prevalence was 10.8% and was significantly higher in females than in males (14.0% vs. 7.1%, p<0.001). In logistic regression analyses, gender (OR=2.48, 95% CI=1.68-3.66) and depression (OR=1.08, 95% CI=1.04-1.12) were significantly linked to irritable bowel syndrome. The prevalence of irritable bowel syndrome in this adolescent population is similar to that reported in other studies. The association of irritable bowel syndrome with depression should guide preventive and therapeutic efforts for this specific age group. © 2015 Turkish Journal of Pediatrics. All rights reserved.Öğe Re: The micturition habits and prevalence of daytime urinary incontinence in Japanese primary school children [5] (multiple letters)(Lippincott Williams and Wilkins, 2004) Baysoy, Gökhan; Aydoğmuş, Tuğba; Akın, Demet; Uyan, Ayten P.f late urinary retention following brachytherapy and found as predictive factors age greater than 65 years and a planning prostate volume of more than 35 cc. The authors quote our group as reporting on 82 similarly treated patients without development of urethral strictures during a median followup of 24 months.1 Our group further reported data on 230 patients with a median followup of 40 months in 2002 regarding late grade 3 to 4 toxicity (Radiation Therapy Oncology Group criteria) in 12.2% of patients. Of our patients 7.4% had development of urethral strictures and 3% had grade 2 to 3 incontinence. In addition, we reported 1.7% of patients had development of a rectourethral fistula after rectal ulceration requiring colostomy.2 All patients with rectourethral fistula underwent rectal biopsy 1 year after treatment, and, therefore, there appears to be an increased risk when biopsies are taken from the anterior rectal wall after high dose rate brachytherapy. In our experience patients undergoing transurethral prostatectomy or urethrotomy within 1 year are at higher risk for grade 3 to 4 complications.