Postmenopozal osteoporozda depresyonun demografik özellikleri kemik mineral yoğunluğu ve yaşam kalitesi arasındaki ilişkinin incelenmesi
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Dosyalar
Tarih
2003
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Cilt Başlığı
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Bu çalışmanın amacı, postmenopozal osteoporotik kadınlarda depresyonun kemik kaybı ile yaşam kalitesine olan etkisini araştırmaktır. Bu çalışmaya 72 kadın hasta alınmıştır (ortalama yaş 654-/- 6.9). Bu hastaların 27'sinde depresyon tespit edildi ( 37.5%) ve 45'inin depresyonu yoktu (62.5 %). Bütün hastalar, DEXA, Hamilton depresyon skalası, Short Form-36 (SF-36)ve Vizüel Analog Skalası ile değerlendirildiler. Depresyonlu hastalarda, L1-L4 T skor (-3.29+/- 1.07), Femur total T skor (-2.60+/-1.00) ve Z skor (-0.97+/-0.82) değerleri , depresyonu olmayan hastalardaki değerlere göre (sırasıyla, -2.71 +/-0.83, -1.86+/-1.16 ve -0.50+/-0.91) anlamlı olarak düşük idi. SF-36 skorları depresyonlu hastalarda (75.9+/-19.8) depresyonsuz hastalara göre (86.5+/-14.4) daha düşük saptandı (p= 0.041). Hamilton skoru ile L1-4 Z skoru (R= -0.432, p=0.024), Femur total T skoru (RO-0.528, p= 0.005) arasında negatif korelasyon bulundu. Sonuç olarak, depresyonlu hastalarda postmenopozal kemik kaybının daha fazla ve fonksiyonel kapasitenin ise daha düşük olduğu sonucuna varıldı.
The aim of this study was to determined the effects of depression on bone loss and quality of life in postmenopausal osteoporotic (PMO) women. Seventy two females (mean age 65 ± 6.9) were included in this study. Out of these patients, 27 (37.5%) had depression, 45 (62.5%) were normal. All cases were evaluated by DXA, Hamilton depression scale, Short Form-36 (SF-36) scale and visual analog scale. In the patients with depression, L1-L4 t-score (-3.29 ± 1.07), femur neck t-score (-2.60 ± 1.00) and z-score (- 0.97 ± 0.82) were significantly lower than PMO patients without depression (respectively; -2.71 ± 0.83, -1.86 ± 1.16 and –0.50 ± 0.91). SF-36 scores (75.9 ± 19.8) were lower in patients with depression than patients without depression (86.5 ± 14.4) (p=0.041). Negative correlations between Hamilton score and L1-L4 z-score (R=-0.432, p=0.024), femur neck t-score (R=-0.528, p=0.005) were found. In conclusion, postmenopausal bone loss was higher and functional capasity was lower in patients with depression.
The aim of this study was to determined the effects of depression on bone loss and quality of life in postmenopausal osteoporotic (PMO) women. Seventy two females (mean age 65 ± 6.9) were included in this study. Out of these patients, 27 (37.5%) had depression, 45 (62.5%) were normal. All cases were evaluated by DXA, Hamilton depression scale, Short Form-36 (SF-36) scale and visual analog scale. In the patients with depression, L1-L4 t-score (-3.29 ± 1.07), femur neck t-score (-2.60 ± 1.00) and z-score (- 0.97 ± 0.82) were significantly lower than PMO patients without depression (respectively; -2.71 ± 0.83, -1.86 ± 1.16 and –0.50 ± 0.91). SF-36 scores (75.9 ± 19.8) were lower in patients with depression than patients without depression (86.5 ± 14.4) (p=0.041). Negative correlations between Hamilton score and L1-L4 z-score (R=-0.432, p=0.024), femur neck t-score (R=-0.528, p=0.005) were found. In conclusion, postmenopausal bone loss was higher and functional capasity was lower in patients with depression.
Açıklama
Anahtar Kelimeler
Kemik Mineral Yoğunluğu, Depresyon, Yaşam Kalitesi, Postmenopozal Osteoporoz, Bone Mineral Density, Depression, Quality of Life, Postmenopausal Osteoporosis
Kaynak
Osteoporoz Dünyasından
WoS Q Değeri
Scopus Q Değeri
Cilt
9
Sayı
3
