The role of duodenal jejunal bypass liner in obesity treatment

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Küçük Resim

Tarih

2021

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

AMER INST MATHEMATICAL SCIENCES-AIMS

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Endoscopic bariatric procedures including Duedenal Jejunal Bypass Liner (DJBL) have become widespread in obesity treatment in recent years. The aim of this systematic review was to assess the role of DJBL in obesity treatment. A comprehensive search of several databases, including Cochrane Library, PubMed, and Web of Science was conducted to December 2020. Twenty-four clinical studies were assessed. According to the results, it is clear that DJBL provides effective weight reduction at 6-12 months and significant improvements in parameters associated with metabolic syndrome and cardiovascular disease. This technique also has potential to reduce comedications in patients with obesity and type 2 diabetes. Although these positive effects of DJBL are clear, its effect on liver, pancreatic functions, and inflammation markers are not clear yet. In addition, the overall and serious complication (gastrointestinal bleeds, pancreatitis, hepatic abscess, obstruction of the sleeve, biliary colic without cholecystitis and cholangitis) rate causing from the DJBL is very high. DJBL has not been approved by the Food and Drug Administration due to the frequency and severity of complications it causes. While it is certain that DJBL has significant effects on obesity and obesity related comorbidities, the safety aspect needs to be improved.

Açıklama

Anahtar Kelimeler

Duodenal Jejunal Bypass Liner, Duodenal Jejunal Bypass Sleeve, EndoBarrier, Weight-Loss, Glycemic Control, Metabolic Improvement

Kaynak

Aims Medical Science

WoS Q Değeri

N/A

Scopus Q Değeri

Cilt

8

Sayı

3

Künye

Ülger, T. G., Tayfur, M., Çakıroğlu, F. P., & Özcan, Ç. (2021). The role of duodenal jejunal bypass liner in obesity treatment. AIMS Medical Science, 8(3), 224-236.