The role of duodenal jejunal bypass liner in obesity treatment
Yükleniyor...
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
AMER INST MATHEMATICAL SCIENCES-AIMS
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Endoscopic bariatric procedures including Duedenal Jejunal Bypass Liner (DJBL) have become widespread in obesity treatment in recent years. The aim of this systematic review was to assess the role of DJBL in obesity treatment. A comprehensive search of several databases, including Cochrane Library, PubMed, and Web of Science was conducted to December 2020. Twenty-four clinical studies were assessed. According to the results, it is clear that DJBL provides effective weight reduction at 6-12 months and significant improvements in parameters associated with metabolic syndrome and cardiovascular disease. This technique also has potential to reduce comedications in patients with obesity and type 2 diabetes. Although these positive effects of DJBL are clear, its effect on liver, pancreatic functions, and inflammation markers are not clear yet. In addition, the overall and serious complication (gastrointestinal bleeds, pancreatitis, hepatic abscess, obstruction of the sleeve, biliary colic without cholecystitis and cholangitis) rate causing from the DJBL is very high. DJBL has not been approved by the Food and Drug Administration due to the frequency and severity of complications it causes. While it is certain that DJBL has significant effects on obesity and obesity related comorbidities, the safety aspect needs to be improved.
Açıklama
Anahtar Kelimeler
Duodenal Jejunal Bypass Liner, Duodenal Jejunal Bypass Sleeve, EndoBarrier, Weight-Loss, Glycemic Control, Metabolic Improvement
Kaynak
Aims Medical Science
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
8
Sayı
3
Künye
Ülger, T. G., Tayfur, M., Çakıroğlu, F. P., & Özcan, Ç. (2021). The role of duodenal jejunal bypass liner in obesity treatment. AIMS Medical Science, 8(3), 224-236.