Failure of intravitreal dexamethasone implant application

Intravitreal dexamethasone implantation (IVDI) has been introduced for indications of retinal venous occlusion, diabetic maculopathy and macular edema due to posterior uveitis. A 65-year-old man, who developed bilateral diabetic macular edema and had limited response to bilateral intravitreal anti-vascular endothelial growth factor injections, was planned to undergo bilateral IVDI. The IVDI was performed without any complication in the right eye but it could not be performed in the left eye due to failure of full-scleral access with the implant applicator during IVDI application in the left eye. When the applicator was checked after failed application, it was determined that the implant partially spilled slightly from the conical part of the applicator needle. Controlling applicator needle and implant position prior to IVDI application is important for application success. © 2019 Gazi Eye Foundation. All rights reserved.