The Myocardial Perfusion Scintigraphy in Predicting Risk for Coronary Artery Disease in Patients with Anxiety and Depression Symptoms

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dc.contributor.authorÇalışkan, Billur
dc.contributor.authorKorkmaz, Ayşe Nurdan
dc.contributor.authorYıldırım, Osman
dc.contributor.authorTuman, Taha Can
dc.contributor.authorKayka, Nefise
dc.contributor.authorErdem, Alim
dc.date.accessioned2021-06-23T18:21:55Z
dc.date.available2021-06-23T18:21:55Z
dc.date.issued2016
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractIntroduction: An association between psychological factors and cardiovascular disease, has long been suspected. However, it is not clear whether chest pain is caused by emotional distress or whether coronary spasms are caused by the onset of coronary artery disease (CAD). We aimed to predict the risk for CAD in patients referred to myocardial perfusion imaging (MPI) with chest pain using depression, stress, and anxiety symptoms.Methods: The emotional status of all patients was evaluated using the Hospital Anxiety and Depression Scale (HADS-A and HADS-D), the State and Trait Anxiety Inventory (STAI-1 and STAI-2), the Perceived Stress Scale (PSS), and the Anxiety Sensitivity Index-3 (ASI). Myocardial perfusion was measured using a 17-segment model and 5-point scoring system (0: normal perfusion; 4: no perfusion). Results: MPI revealed reversible perfusion defects in 24 of 141 patients and no perfusion defects in 117 patients. The STAI-2 and HADS-A and HADS-D scores were significantly higher in patients with myocardial ischemia than in those without (STAI-2: 50.8 ± 7.5 vs. 46.3 ± 7.1, respectively; p = 0.008; HADS-A: 9.5 ± 3.9 vs. 7.8 ± 3.4, respectively; p = 0.033; HADS-D: 8.7 ± 3.0 vs. 7.3 ± 3.0, respectively; p = 0.05). Unadjusted correlation analysis showed that there was statistically significant correlation between reversible perfusion defects and anxiety scores (r=0.186, p= 0.029).Conclusion: The patients with symptoms of depression and high-trait anxiety may be at higher risk of myocardial ischemia than patients without such symptoms. Thus, the emotional status of patients should be taken into consideration during clinical evaluation for CAD.en_US
dc.identifier.endpage81en_US
dc.identifier.issn2148-2357
dc.identifier.issn2148-2357
dc.identifier.issue2en_US
dc.identifier.startpage77en_US
dc.identifier.trdizinid200168en_US
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TWpBd01UWTRPQT09
dc.identifier.urihttps://hdl.handle.net/20.500.12491/711
dc.identifier.volume4en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorÇalışkan, Billur
dc.language.isoenen_US
dc.relation.ispartofActa Medica Anatoliaen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGenel ve Dahili Tıpen_US
dc.titleThe Myocardial Perfusion Scintigraphy in Predicting Risk for Coronary Artery Disease in Patients with Anxiety and Depression Symptomsen_US
dc.typeArticleen_US

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