The Myocardial Perfusion Scintigraphy in Predicting Risk for Coronary Artery Disease in Patients with Anxiety and Depression Symptoms
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Tarih
2016
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info:eu-repo/semantics/openAccess
Özet
Introduction: An association between psychological factors and cardiovascular disease, has long been suspected. However, it is not clear whether chest pain is caused by emotional distress or whether coronary spasms are caused by the onset of coronary artery disease (CAD). We aimed to predict the risk for CAD in patients referred to myocardial perfusion imaging (MPI) with chest pain using depression, stress, and anxiety symptoms.Methods: The emotional status of all patients was evaluated using the Hospital Anxiety and Depression Scale (HADS-A and HADS-D), the State and Trait Anxiety Inventory (STAI-1 and STAI-2), the Perceived Stress Scale (PSS), and the Anxiety Sensitivity Index-3 (ASI). Myocardial perfusion was measured using a 17-segment model and 5-point scoring system (0: normal perfusion; 4: no perfusion). Results: MPI revealed reversible perfusion defects in 24 of 141 patients and no perfusion defects in 117 patients. The STAI-2 and HADS-A and HADS-D scores were significantly higher in patients with myocardial ischemia than in those without (STAI-2: 50.8 ± 7.5 vs. 46.3 ± 7.1, respectively; p = 0.008; HADS-A: 9.5 ± 3.9 vs. 7.8 ± 3.4, respectively; p = 0.033; HADS-D: 8.7 ± 3.0 vs. 7.3 ± 3.0, respectively; p = 0.05). Unadjusted correlation analysis showed that there was statistically significant correlation between reversible perfusion defects and anxiety scores (r=0.186, p= 0.029).Conclusion: The patients with symptoms of depression and high-trait anxiety may be at higher risk of myocardial ischemia than patients without such symptoms. Thus, the emotional status of patients should be taken into consideration during clinical evaluation for CAD.
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Genel ve Dahili Tıp
Kaynak
Acta Medica Anatolia
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Cilt
4
Sayı
2
