Complete Blood Count parameters could predict malignancy in breast lesions

Basit Öğe Kaydı
dc.contributor.authorÖzer, Bahri
dc.contributor.authorÇatal, Oğuz
dc.contributor.authorÖzer, Songül Peltek
dc.contributor.authorKeyif, Fatih
dc.contributor.authorŞit, Mustafa
dc.contributor.authorKama, Nuri
dc.date.accessioned2024-09-25T20:16:49Z
dc.date.available2024-09-25T20:16:49Z
dc.date.issued2020
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractAim: Inflammatory response plays an important role in the development and progression of various cancers, including breast cancer.The aim of present study is determining Complete Blood Count parameters as possible predictors of malignancy in breast lesions.Material and Methods: Patients with BI-RADS-4 breast disease were studied between 2010 and 2017 retrospectively. Patients withlesions detected radiologically were included in the study. According to the histopathological results, the study cohort was dividedinto two groups, either benign or malignant. Final blood counts of the patients before pre-biopsy were evaluated in preoperativeperipheral blood measurements. When blood was taken, care was taken not to have other causes of leukocytosis in the patient.Complete Blood Count parameters were compared in these groups.Results: A total of 331 women with BI-RADS 4 lesions enrolled to the study. Mortality and morbidity were not observed after breastbiopsy in patients. Platelet (p=0.04), platelet to lymphocyte ratio (p=0.006) and red cell distribution width to platelet ratio (p=0.032)values of the patients with BI RADS 4A were found significantly different in the malignant group compared to benign BI RADS 4Agroup. In total BIRADS 4 lesions, the ratio of PLT and RPR was significant in malignant group (p=0.047, p=0.002) in Complete BloodCount parameters compared benign and malignant group.Conclusion: Studies have shown that cancer affects peripheral blood cells positively or negatively. In our study, among peripheralblood cells, platelets were found to be the most affected in cancer patients. The PLT, PLR and RPR values could be valuable inpredicting malignant BIRADS 4 breast lesions.en_US
dc.identifier.doi10.5455/annalsmedres.2020.02.150
dc.identifier.endpage2137en_US
dc.identifier.issn2636-7688
dc.identifier.issue8en_US
dc.identifier.startpage2134en_US
dc.identifier.trdizinid383368en_US
dc.identifier.urihttps://doi.org/10.5455/annalsmedres.2020.02.150
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/383368
dc.identifier.urihttps://hdl.handle.net/20.500.12491/15225
dc.identifier.volume27en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzYK_20240925en_US
dc.titleComplete Blood Count parameters could predict malignancy in breast lesionsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu