Potentialities of nanosilver-based thin film coatings for medical device and implants
Küçük Resim Yok
Tarih
2024
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The physicochemical properties of a biomaterial surface, together with the antifouling property of the device, that is, its long-term antibacterial performance, are crucial for developing new coating technologies without toxic effects on mammalian cells and without causing drug resistance. Nanotechnology-based strategies hold promise for preventing drug-resistant biofilm infections of biomaterials and medical devices. One of the best methods for minimizing hospital-acquired infections is to use biocompatible antimicrobial polymers whose surfaces are modified by biocidal substances, such as antimicrobial peptides, antibiotics, and silver nanoparticles. Nanosilver is the most effective metal with superior antimicrobial properties, because of its oligodynamic effect, versatile biocidal mechanisms of action, and low cytotoxicity for humans. Comprehensive information on various surface modification methods for biomaterial coatings that can be utilized to fix silver nanoparticles on polymer-based composites of both synthetic and natural origin, which are candidates for medical devices and implants was provided in this chapter. Finally, the issues about safety concerns, potential toxicity, and compatibility of AgNPs-polymeric nanocomposites used in biomedical devices and implants were discussed. © 2024 Elsevier Ltd. All rights reserved.
Açıklama
Anahtar Kelimeler
Antibacterial, biomedical implants, cytotoxicity, silver nanoparticles, surface modification
Kaynak
Next-Generation Antimicrobial Nanocoatings for Medical Devices and Implants
WoS Q Değeri
Scopus Q Değeri
N/A
