Five-year experience of neurosyphilis cases in a tertiary care hospital in Turkey

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dc.authorid0000-0001-5524-5767
dc.contributor.authorOgun, Muhammed Nur
dc.contributor.authorSırmatel, Fatma
dc.date.accessioned2021-06-23T18:27:17Z
dc.date.available2021-06-23T18:27:17Z
dc.date.issued2019
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractAim: To evaluate retrospectively the cases of syphilis who applied to different clinics of our hospital in the last 5 years and to emphasize the importance of admission screening tests in the diagnosis of neurosyphilis which is a rare but serious form of syphilis. Methods: Sixty-one patients who admitted to different clinics of our hospital between 2013 and 2017 with different clinical manifestations and positive Venereal Disease Research Laboratory (VDRL) and Treponema pallidum microhemagglutination assay (TPHA) tests were recorded and analyzed retrospectively. Results: Both VDRL and TPHA tests were positive in 44 males with a mean age of 57.4 ± 18.4 years and 17 females with a mean age of 65.3 ± 19.1 years. It was found that of the 61 patients who were examined for differential diagnosis of syphilis, 36 (%59) of them were referred from neurology clinic, 15 (25%) from infectious diseases clinic, 7 (12%) from dermatology clinic and 3 (4%) from gynecology clinic. The clinical presentation was venereal chancre in 15 cases, asymptomatic ischemic brain lesions in 17 cases, acute ischemic stroke in 13 cases, movement disorder in three cases, tabes dorsalis in two cases, tendinitis-arthritis in eight cases, Amyotrophic lateral sclerosis (ALS) in one case, Deep venous thrombosis (DVT) in one case, and pulmonary nodule in one case. Conclusions: In conclusion, syphilis is often overlooked in the differential diagnosis in patient with neurological findings. Since neurosyphilis is an easily treatable disease, it should be considered in the differential diagnosis of patients presenting with neurological findings.en_US
dc.identifier.doi10.30714/j-ebr.2019454853
dc.identifier.endpage162en_US
dc.identifier.issn2618-6454
dc.identifier.issn2618-6454
dc.identifier.issue4en_US
dc.identifier.startpage158en_US
dc.identifier.trdizinid367274en_US
dc.identifier.urihttps://doi.org/10.30714/j-ebr.2019454853
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TXpZM01qYzBOQT09
dc.identifier.urihttps://hdl.handle.net/20.500.12491/1633
dc.identifier.volume2en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorOgun, Muhammed Nur
dc.institutionauthorSırmatel, Fatma
dc.language.isoenen_US
dc.relation.ispartofExperimental Biomedical Researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectNeurosyphilis
dc.subjectSyphilis
dc.subjectTertiary Syphilis
dc.subjectVDRL
dc.subjectTPHA
dc.titleFive-year experience of neurosyphilis cases in a tertiary care hospital in Turkeyen_US
dc.typeArticleen_US

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