Insulin-like growth factor (IGF-I) in Mauriac syndrome or diabetic dwarfism

Basit Öğe Kaydı
dc.authorid0000-0003-0120-9976
dc.contributor.authorŞimşek, Enver
dc.contributor.authorKocabay, Kenan
dc.date.accessioned2021-06-23T18:40:22Z
dc.date.available2021-06-23T18:40:22Z
dc.date.issued2002
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractMauriac syndrome is characterized by the development of dwarfism, obesity and hepatomegaly in patients with insulin dependent diabetes mellitus (1). Growth retardation and hepatomegaly in diabetes mellitus should alert physicians over the insufficient management of diabetes mellitus and the related development of Mauriac syndrome. The cause of growth failure in Mauriac syndrome has remained obscure, although it is presumably related to the poor metabolic control of diabetes (2). Growth hormone deficiency has not been found in reported cases of Mauriac syndrome (3,4). The most important growth promoting effect of growth hormone is mediated by IGF-I (5). The determination of IGF-I and insulin-like growth factor binding protein 3 (IGF-3) had become a widely used tool in the diagnostic evaluation of growth disorders. Although IGF-I levels are commonly considered an indication of growth hormone (GH) secretion or action, its synthesis and secretion are regulated by a multifactorial and complex mechanism. Nutrition, insulin, sex steroids, cortisol, and thyroxin have positive stimulatory effects on the release of IGF-I (6). We report on two cases of diabetes mellitus associated with Mauriac syndrome and limited joint mobility.
dc.identifier.endpage424en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue5en_US
dc.identifier.startpage421en_US
dc.identifier.trdizinid19776en_US
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TVRrM056WTI
dc.identifier.urihttps://hdl.handle.net/20.500.12491/3079
dc.identifier.volume32en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorŞimşek, Enver
dc.institutionauthorKocabay, Kenan
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Medical Sciencesen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectInsulin-Like Growth Factoren_US
dc.subjectMauriac Syndrome
dc.subjectİnsülin Benzeri Büyüme Faktörü
dc.subjectMauriac Sendromu
dc.titleInsulin-like growth factor (IGF-I) in Mauriac syndrome or diabetic dwarfismen_US
dc.typeReporten_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
enver-simsek-3079.pdf
Boyut:
70 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam metin / Full text
İndir

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu
Dahili Tıp Bilimleri Bölümü Koleksiyonu