Evaluation of the neutrophil-lymphocyte ratio and mean platelet volume in hypertensive patients with coronary artery ectasia

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dc.authorid0000-0003-1784-3584
dc.authorid0000-0002-1443-4307
dc.authorid0000-0001-6595-7493
dc.authorid0000-0001-9532-8241
dc.authorid0000-0002-5090-7247
dc.contributor.authorİnanır, Mehmet
dc.contributor.authorAlıcı, Gökhan
dc.contributor.authorAcar, Emrah
dc.contributor.authorEren, Hayati
dc.contributor.authorGürler, Müjgan
dc.contributor.authorAlan, Sait
dc.date.accessioned2021-06-23T18:33:42Z
dc.date.available2021-06-23T18:33:42Z
dc.date.issued2020
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractIntroduction: Coronary artery ectasia (CAE) is associated with increased morbidity and mortality, and is known to also be associated with atherosclerosis. CAE is considered a variant of coronary artery disease, and is more common in patients with hypertension. We aimed to evaluate the neutrophil-lymphocyte ratio (NLR) and mean platelet volume (MPV) in hypertensive patients with CAE.Patients and Methods: The study was designed retrospectively in the cardiology unit of Bolu Abant Izzet Baysal University Medical Faculty Hospital between January 2017 and October 2019. A total of 7287 coro-nary angiographies were retrospectively analyzed to detect the incidence of ischemic heart disease. Diagnosis of CAE was made visually by two cardiologists who were blinded to the study aims. All included patients had a diagnosis of hypertension. After appropriate exclusions, hypertensive patients were divided into CAE and normal coronary artery groups, and the laboratory parameters of the two groups were compared.Results: The neutrophil counts [4.2 (2.4-8.6) vs. 4.2 (2.0-6.7) u/mm3, p= 0.015], red cell distribution width [15.7 (12.8-21.6) vs. 15.3 (13.2-18.6) %, p= 0.002], platelet distribution width [17.9 (15.5-23.0) vs. 17.5 (15.9-20.8) %, p= 0.001], NLR [2.1 (0.7-12.8) vs. 1.9 (0.8-4.5), p< 0.001], platelet-lymphocyte ratio [109.8 (63.0-321.8) vs. 100.9 (34.7-223.6), p= 0.001], MPV (8.4 ± 1.4 vs. 7.9 ± 1.0 fL, p< 0.001), and plateletcrit (0.19 ± 0.05 vs. 0.18 ± 0.4 %, p= 0.007) were significantly higher, and the lymphocytes counts [2.1 (0.5-4.2) vs. 2.2 (1.1-6.7) u/mm3, p= 0.013] were significantly lower in hypertensive patients with CAE than in those without.Conclusion: Hemogram parameters could be useful biomarkers for determining a thrombotic state and in-flammatory response in hypertensive patients with CAE.en_US
dc.identifier.doi10.5578/khj.69504
dc.identifier.endpage63en_US
dc.identifier.issn2149-2972
dc.identifier.issn2149-2980
dc.identifier.issue1en_US
dc.identifier.startpage59en_US
dc.identifier.trdizinid365688en_US
dc.identifier.urihttps://doi.org/10.5578/khj.69504
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TXpZMU5qZzRPQT09
dc.identifier.urihttps://hdl.handle.net/20.500.12491/2312
dc.identifier.volume23en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorİnanır, Mehmet
dc.institutionauthorGürler, Müjgan
dc.institutionauthorAlan, Sait
dc.language.isoenen_US
dc.relation.ispartofKoşuyolu Heart Journalen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCoronary Artery Ectasia
dc.subjectHypertension
dc.subjectInflammation
dc.subjectMean Platelet Volume
dc.subjectNeutrophil-Lymphocyte Ratio
dc.subjectHipertansiyon
dc.subjectİnflamasyon
dc.subjectKoroner Arter Ektazi
dc.subjectNötrofil-Lenfosit Oranı
dc.subjectOrtalama Trombosit Hacmi
dc.titleEvaluation of the neutrophil-lymphocyte ratio and mean platelet volume in hypertensive patients with coronary artery ectasiaen_US
dc.typeArticleen_US

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