The relation between antiepileptic drug type and cognitive functions in childhood epilepsy: A Prospective observational study

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dc.authorid0000-0002-1019-9207
dc.authorid0000-0002-2197-8433
dc.authorid0000-0001-9904-6479
dc.authorid0000-0001-5896-074X
dc.contributor.authorHancı, Fatma
dc.contributor.authorCanpolat, Mehmet
dc.contributor.authorPer, Hüseyin
dc.contributor.authorGümüş, Hakan
dc.contributor.authorKumandas, Sefer
dc.date.accessioned2021-06-23T18:27:15Z
dc.date.available2021-06-23T18:27:15Z
dc.date.issued2019
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractAim: This study investigated the effect of antiepileptic drug monotherapy on cognitive functions in pediatric epilepsy patients. Methods: 98 recently diagnosed epilepsy patients aged 6-16 years were included. All patients underwent routine laboratory tests, electroencephalography, brain magnetic resonance imaging, and intelligence testing. The patients were treated with valproic acid (VA), carbamazepine (CBZ), oxcarbazepine (OXC), or levetiracetam (LEV). The Wechsler Intelligence Scale for Children (WISCR) was applied three times, before, six months and 12 months after the start of antiepileptic therapy. Results: No significant difference was determined among the mean verbal, performance and total intelligence scores of patients using a single antiepileptic drug at baseline, after six or 12 months. Conclusion: We conclude that the type of antiepileptic drug using has no adverse effects on cognitive functions.en_US
dc.identifier.doi10.30714/j-ebr.2019250351
dc.identifier.endpage68en_US
dc.identifier.issn2618-6454
dc.identifier.issn2618-6454
dc.identifier.issue2en_US
dc.identifier.startpage62en_US
dc.identifier.trdizinid370404en_US
dc.identifier.urihttps://doi.org/10.30714/j-ebr.2019250351
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TXpjd05EQTBOQT09
dc.identifier.urihttps://hdl.handle.net/20.500.12491/1629
dc.identifier.volume2en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorHancı, Fatma
dc.language.isoenen_US
dc.relation.ispartofExperimental Biomedical Researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEpilepsy
dc.subjectAntiepileptic Drugs
dc.subjectCognitive Functions
dc.subjectWISC-R
dc.subjectChildhood
dc.titleThe relation between antiepileptic drug type and cognitive functions in childhood epilepsy: A Prospective observational studyen_US
dc.typeArticleen_US

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