Effect of Total Isoflavones Found in Soybean on Vitellogenin Production in Common Carp

Basit Öğe Kaydı
dc.contributor.authorTurker, Hakan
dc.contributor.authorBozcaarmutlu, Azra
dc.date.accessioned2024-09-25T19:57:27Z
dc.date.available2024-09-25T19:57:27Z
dc.date.issued2009
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractSoybean meal is used most extensively as a replacement to fishmeal as the main protein source in fish diets. However. there is concern about the effect of soybean-based diets on reproductive development of the fish because of the phytoestrogenic properties of soybean. The objective of the present study was to determine whether a relationship exists between the concentration of soybean extract containing total isoflavones in diet and the production of vitellogenin protein in cyprinid fish. Five different doses (0, 250, 500, 1,000, and 10,000 mg/kg based on total isoflavones content) of commercial soybean extract were tested to determine the effect of pyhtoestrogens concentration on vitellogenin synthesis in female and male carp. Cyprinius carpio L. There were no significant differences in the growth of fish between any of the groups All concentrations of soybean extract lowered male gonadosomatic index (GSI). but female GSI was increased in diets including up to 500 mg/kg soybean extract, and then decreased at higher doses. This was associated by an inhibition and induction, respectively. in plasma vitellogenin levels. Changes in GSI and vitellogenin appeared to be sensitive marker for detecting phytoestrogens exposure. Higher concentrations of isoflavones resulted in a higher amount of vitellogenin produced in both male and female fish. Our results clearly showed that exposure to phytoestrogens found in soybean extract significantly induces vitellogenin production in both males and females, in a dose-response manner. GSI and high vitellogenin production indicated that phytoestrogens found in soybean disrupt the endocrine system of fish. The endocrine disruptor effect of soybean products must be considered in fish meal preparation.en_US
dc.description.sponsorshipThe Scientific and Technical Research Council of Turkey, TUBITAK [104Y083]en_US
dc.description.sponsorshipWe wish to thank Prof.Dr. Emel Arinc for her technical support. Part of the present study was supported by a grant from The Scientific and Technical Research Council of Turkey, TUBITAK (Project No: 104Y083). We also thank to Karina M. Bedrack (Global Marketing & Sales Manager-Isoflavones, Solbar Plant Extracts Ltd., Ashdod, Israel) for providing soybean extract.en_US
dc.identifier.endpage568en_US
dc.identifier.issn1300-6045
dc.identifier.issue4en_US
dc.identifier.startpage561en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/13427
dc.identifier.volume15en_US
dc.identifier.wosWOS:000271098600013en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherKafkas Univ, Veteriner Fakultesi Dergisien_US
dc.relation.ispartofKafkas Universitesi Veteriner Fakultesi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzYK_20240925en_US
dc.subjectCommon carpen_US
dc.subjectIsoflavonesen_US
dc.subjectSoybeanen_US
dc.subjectGonadosomatic indexen_US
dc.subjectPhytoestrogenen_US
dc.subjectVitellogeninen_US
dc.titleEffect of Total Isoflavones Found in Soybean on Vitellogenin Production in Common Carpen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu