Neutrophil - lymphocyte ratio in patients with ankylosing spondylitis
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Tarih
2014
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info:eu-repo/semantics/openAccess
Özet
Amaç: Bu çalışmanın amacı, ankilozan spondilit (AS) hastalarındaki inflamasyon ile nötrofil -lenfosit oranı (NLO) arasındaki ilişkiyi belirlemektir. Yöntem: Ankilozan spondilit tanılı 40 hasta ve 30 sağlıklı gönüllü çalışmaya dahil edildi. Tüm veriler yatan ve poliklinik hasta kayıt veritabanından elde edildi. Tüm olguların Bath Ankilozan Spondilit Hastalık Aktivite İndeksi (BA S- DAI), tam kan sayımı (TKS), CRP ve ESH’ı da kapsıyan ayrı ntılı fizik muayene ve laboratuvar bulguları kaydedildi. Lenfosit ve nötrofil sayısı otomatik TKS’nin bir parçası olarak ölçüldü. Bulgular : Akut-faz reaktanı olan CRP ve ESH kontrol gr ubuna göre hasta grubunda anlamlı olarak daha yüksekti (p 0.05). Sonuç : Bu çalışmada NLO düzeylerinin AS hastalarında sağlıklı bireylere göre anlamlı olarak yüksek olmadığı görüldü. Bu sonuç NLO’nun AS hastalarında sistemik in flamasyonu değerlendirmede uygun bir ölçü birimi olmad ığını götermektedir. Bizim elde ettiğimiz bu ön sonuçların daha ileri çalışmalarla tamamlanması gerektiğine inanıyoruz.
Objective : The purpose of the present study is to determine the association between neutrophil -lymphocyte ratio (NLR) and inflammation in ankylosing spondylitis (AS). Method : Forty patients with ankylosing spondylitis and 30 healthy volunteers were included in the study. All data were obtained from patient registry database from in -patient and out-patient clinics. Detailed physical examination, and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) were record ed. Complete blood count (CBC), CRP and ESR were performed recorded as laboratory tests in all participants. Lymphocyte and neutrophil counts were measured as part of the automated CBC. Results : The CRP, which is an acute -phase reactant, and ESR were signi ficantly higher in the patient group than those in the control group (p0.05). Conclusion : We observed that NLR levels weren’t significantly higher in AS patients compared to healthy individuals. NLR hasn’t seem a reasonable measure to detect systemic infla m- mation in AS patients. We believe that our preliminary results need to be complemented with further studies.
Objective : The purpose of the present study is to determine the association between neutrophil -lymphocyte ratio (NLR) and inflammation in ankylosing spondylitis (AS). Method : Forty patients with ankylosing spondylitis and 30 healthy volunteers were included in the study. All data were obtained from patient registry database from in -patient and out-patient clinics. Detailed physical examination, and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) were record ed. Complete blood count (CBC), CRP and ESR were performed recorded as laboratory tests in all participants. Lymphocyte and neutrophil counts were measured as part of the automated CBC. Results : The CRP, which is an acute -phase reactant, and ESR were signi ficantly higher in the patient group than those in the control group (p0.05). Conclusion : We observed that NLR levels weren’t significantly higher in AS patients compared to healthy individuals. NLR hasn’t seem a reasonable measure to detect systemic infla m- mation in AS patients. We believe that our preliminary results need to be complemented with further studies.
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