High voltage pulse generator for pulsed electric field treatments

In food processing, biotechnology and medicine, pulsed electric field (PEF) applications are used in studies on increasing the permeability of the cell membrane or inactivation of microorganisms. PEF applications require high voltage pulse generators. PEF generators are designed depending on the application types. In this study, design and analysis of Metal Oxide Field Effect Transistor (Mosfet) based high voltage impulse generator for biology and medicine were studied. Two scenarios are considered for analysis. In the first scenario, a parallel connected Mosfet based pulse generator with 1400 V amplitude was analyzed. In the second scenario, a series connected Mosfet based pulse generator with 2500 V amplitude was analyzed. The results of the analysis were briefly compared. © 2019 IEEE.