The role of prolactin in psoriasis

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dc.authorscopusid7003782809
dc.authorscopusid7003901757
dc.authorscopusid6603026387
dc.authorscopusid57224433905
dc.authorscopusid55403695600
dc.contributor.authorYavuz, Özlem
dc.contributor.authorKavak, Ayşe
dc.contributor.authorParlak, Ali Haydar
dc.contributor.authorAnil, Hüseyin
dc.contributor.authorAydo?an, Iilker
dc.date.accessioned2024-09-25T19:45:16Z
dc.date.available2024-09-25T19:45:16Z
dc.date.issued2002
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractBackground: Despite its well known a variety of biological activities, it has been suggested that prolactin acts as an important in vivo modulator of cellular and humoral immunity and has some effects about skin epithelial cell proliferation and skin immune system. Objective: It was studied whether the relationship between psoriasis, which is a common inflammatory skin disease of still obscure etiology characterized by epidermal hyperplasia and dyskeratinization, and serum levels of prolactin. Materials and Methods: Serum levels of prolactin were estimated in 34 patients with psoriasis and the results were compared with those in 21 normal control subjects. Serum levels of prolactin were measured with chemiluminescent enzyme immunometric assay by using DPC commercial kits on Immulite One hormone analyser. Results: When serum prolactin levels in patients with psoriasis (mean ± SD: 8,9±5,4 ng/ml) were compared with those in normal control subjects (mean ± SD: 9,13±5,18 ng/ml), it was no significant difference between two groups (p= 0.548). Conclusion: In recent years, it has become apparent that prolactin plays an important part in the immune reactions and exerts a proliferative effect on human keratinocytes. But in our study, serum prolactin levels were not found significantly higher in patients with psoriasis. When it was took into consideration that there were powerful data supported the role of prolactin in epithelial proliferation and immunoregulation, it was thought that it should be performed further studies on this topic.en_US
dc.identifier.endpage267en_US
dc.identifier.issn1019-214X
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-0141427707en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage263en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/12942
dc.identifier.volume36en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofTurkderm Deri Hastaliklari ve Frengi Arsivien_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzYK_20240925en_US
dc.subjectKeratinocyte proliferationen_US
dc.subjectProlactinen_US
dc.subjectPsoriasisen_US
dc.titleThe role of prolactin in psoriasisen_US
dc.title.alternativePsoriasisde prolaktinin rolü]en_US
dc.typeConference Objecten_US

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