Is there any relationship between serum ?-glutamyltransferase levels and premature coronary artery disease?

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dc.authoridErdem, Kemalettin/0000-0002-1012-837X
dc.authoridDonmez, Ibrahim/0000-0002-6913-9073
dc.authoridAlcelik, Aytekin/0000-0002-3156-1076
dc.contributor.authorOzlu, Mehmet Fatih
dc.contributor.authorAyhan, Suzi Selim
dc.contributor.authorErdem, Alim
dc.contributor.authorTosun, Mehmet
dc.contributor.authorOzturk, Serkan
dc.contributor.authorErdem, Kemalettin
dc.contributor.authorOzyasar, Mehmet
dc.date.accessioned2024-09-25T19:58:35Z
dc.date.available2024-09-25T19:58:35Z
dc.date.issued2012
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractBackground: The relationship between gamma-glutamyltransferase (GGT) and coronary artery disease (CAD) has been revealed in several previous studies. However, the relationship between the severity of CAD and GGT levels has not been previously studied in a premature group (< 40 years old). Aim: We aim to investigate whether GGT is associated with premature CAD. Material and methods: The study population consisted of 181 premature coronary artery disease patients (group 1; mean age: 36.5 +/- 2.5 years) and 80 controls (group 2; mean age: 37.2 +/- 2.3 years). The severity of CAD in group 1 was evaluated by the Gensini scoring system. gamma-Glutamyltransferase levels and the other basic biochemical parameters were analyzed, and relations with severity of CAD were evaluated. Results: There were no statistically significant differences in serum GGT activity between the two groups (p > 0.05). gamma-Glutamyltransferase levels in group 1 were found not to be correlated with the severity of premature CAD (r = -0.016, p = 0.828). Furthermore, in subgroup analyses we found glycated hemoglobin (HbA(1c)) levels significantly correlated with the severity of CAD in diabetic premature CAD patients, but not GGT (r = 0.448, p < 0.001; r = 0.157, p = 0.127, respectively). Conclusions: gamma-Glutamyltransferase level was not associated with severity of CAD in the premature group. Possibly, there is no predictive importance of GGT in patients with premature CAD.en_US
dc.identifier.doi10.5114/pwki.2012.29650
dc.identifier.endpage101en_US
dc.identifier.issn1734-9338
dc.identifier.issn1897-4295
dc.identifier.issue2en_US
dc.identifier.startpage96en_US
dc.identifier.urihttps://doi.org/10.5114/pwki.2012.29650
dc.identifier.urihttps://hdl.handle.net/20.500.12491/13633
dc.identifier.volume8en_US
dc.identifier.wosWOS:000306728300004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.institutionauthorDonmez, Ibrahim
dc.language.isoenen_US
dc.publisherTermedia Publishing House Ltden_US
dc.relation.ispartofPostepy W Kardiologii Interwencyjnejen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzYK_20240925en_US
dc.subjectgamma-glutamyltransferaseen_US
dc.subjectprematureen_US
dc.subjectcoronary artery diseaseen_US
dc.subjectGensini scoreen_US
dc.titleIs there any relationship between serum ?-glutamyltransferase levels and premature coronary artery disease?en_US
dc.typeArticleen_US

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