Diagnostic Value of HALP Score in Detecting Diabetic Nephropathy in Patients with Type 2 Diabetes Mellitus

Basit Öğe Kaydı
dc.authoridAktas, Gulali/0000-0001-7306-5233
dc.authoridDuman, Tuba/0000-0002-3836-2125
dc.authoridAtak, Burcin Meryem/0000-0003-4201-9757
dc.contributor.authorTel, Burcin Meryem Atak
dc.contributor.authorTel, Mustafa Ramiz
dc.contributor.authorBilgin, Satilmis
dc.contributor.authorDuman, Tuba Taslamacioglu
dc.contributor.authorAktas, Gulali
dc.date.accessioned2024-09-25T19:58:36Z
dc.date.available2024-09-25T19:58:36Z
dc.date.issued2024
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractIntroduction Hemoglobin, albumin, lymphocyte, and platelet (HALP) score has been used to predict the prognosis in several types of cancers for the last few years. We aimed to reveal whether HALP score has high sensitivity and specificity in the detection of diabetic nephropathy. Methods A cross-sectional study developed in Abant Izzet Baysal University Hospital in Bolu, Turkiye. Patients with type 2 diabetesmellitus (DM) were enrolled in the study. Study cohort included patients with diabetic nephropathy and patients without diabetic nephropathy. Pregnant women, subjects with malignancy, active infections conditions, and rheumatologic or hematologic diseases were excluded. We retrospectively analyzed and compared the HALP scores of the type 2 DM patients with and without diabetic nephropathy. Moreover, we sought correlation between HALP score and fasting glucose, glycated hemoglobin (HbA1c), and estimated glomerular filtration rate (eGFR). Results A total of 356 DM patients, 162 with nephropathy and 194 without nephropathy were included in the study. The HALP score was 44.86 (4.5-119.9) in the nephropathic group, while it was 55.14 (13.2-173.7) in the nonnephropathic group (p < 0.001). HALP score was negatively correlated with HbA1c (r = -0.66, p - 0.003) and fasting glucose (r = -0.65, p = 0.002), while positive correlation was found between HALP score and eGFR (r = 0.13, p = 0.02). HALP score lower than 45.9% have 73% sensitivity and 52% specificity in detecting diabetic nephropathy (area under the curve: 0.64, p<0.001, 95% confidence interval: 0.59-0.70). Conclusion We suggest that HALP score can become a simple and easy to assess marker for diabetic nephropathy in addition to standard tests.en_US
dc.identifier.doi10.1055/s-0044-1787998
dc.identifier.endpage122en_US
dc.identifier.issn1947-489X
dc.identifier.issue3en_US
dc.identifier.startpage116en_US
dc.identifier.urihttps://doi.org/10.1055/s-0044-1787998
dc.identifier.urihttps://hdl.handle.net/20.500.12491/13653
dc.identifier.volume16en_US
dc.identifier.wosWOS:001280127600001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherThieme Medical Publ Incen_US
dc.relation.ispartofIbnosina Journal of Medicine And Biomedical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzYK_20240925en_US
dc.subjectHALP scoreen_US
dc.subjecttype 2 diabetes mellitusen_US
dc.subjectmicrovascular complicationen_US
dc.subjectdiabetic nephropathyen_US
dc.subjectmarkeren_US
dc.titleDiagnostic Value of HALP Score in Detecting Diabetic Nephropathy in Patients with Type 2 Diabetes Mellitusen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu