Evaluation of retinal, retinal nerve fiber layer and choroidal thicknesses in diabetic patients without diabetic retinopathy

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dc.authorscopusid6506789098
dc.authorscopusid57215431649
dc.authorscopusid56007692400
dc.authorscopusid55794511600
dc.authorscopusid8065719600
dc.authorscopusid6507309090
dc.contributor.authorUlaş, Fatih
dc.contributor.authorDoğan, Ümit
dc.contributor.authorÇelik, Fatih
dc.contributor.authorSoydan, Adem
dc.contributor.authorÇelebi, Serdal
dc.contributor.authorDikbaş, Oğuz
dc.date.accessioned2024-09-25T19:43:17Z
dc.date.available2024-09-25T19:43:17Z
dc.date.issued2015
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractPurpose: Comparison of retinal, retinal nerve fiber layer (RNFL) and choroidal thicknesses in healthy subjects and diabetic patients without retinopathy. Materials and Methods: The study included 133 diabetic patients without diabetic retinopathy and 60 healthy subjects aging 37-78 years of age. Horizontal line scan of retina and choroid were performed using enhanced depth imaging mode of Fourier domain optical coherence tomography. The retinal and choroidal thicknesses were measured at the central fovea and at 1500 µm nasal and 1500 µm temporal from the center of the fovea. RNFL thickness measurements were performed using default RNFL thickness measurement mode provided by the device. Results: The mean age of diabetic group and control group were 52.75±12.74 and 53.83±5.95 years, respectively. Intraocular pressure (IOP) of diabetic group and control group were 16.26±2.90 and 13.18±2.13 mmHg, respectively (p<0.001). Central retinal thickness of diabetic group and control group were 226.24±18.78 and 216.37±14.79 µm, respectively (p<0.001). Subfoveal choroidal thickness of diabetic group and control group were 301.95±76.20 and 346.62±82.14 µm, respectively (p=0.001). We did not determine statistically significant difference between RNFL thicknesses of the groups (p=0.494). Correlation analysis using Spearman test revealed presence of diabetes showed association with increased foveal retinal thickness, decreased subfoveal choroidal thickness and increased IOP (range of rho values were -0.262 and 0.543, p<0.001). Conclusions: Diabetic group had higher retinal thickness, lower choroidal thickness and higher IOP values compared to healthy subjects. No significant RNFL thickness difference was determined between the groups. Results of the current study demonstrated that IOP and posterior segment of diabetic patients without retinopathy should be evaluated cautiously. © 2015 Gazi Eye Foundation. All Rights Reserved.en_US
dc.identifier.endpage335en_US
dc.identifier.issn1300-1256
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85062464381en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage331en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/12518
dc.identifier.volume23en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherGazi Eye Foundationen_US
dc.relation.ispartofRetina-Vitreusen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzYK_20240925en_US
dc.subjectChoroidal thicknessen_US
dc.subjectDiabetes mellitusen_US
dc.subjectIntraocular pressureen_US
dc.subjectRetinal nerve fiber layer thicknessen_US
dc.subjectRetinal thicknessen_US
dc.titleEvaluation of retinal, retinal nerve fiber layer and choroidal thicknesses in diabetic patients without diabetic retinopathyen_US
dc.title.alternativeDiyabetik retinopati Gelişmemiş diyabetik olgularda retina, Retina sinir lifi tabakası ve koroid kalınlığının değerlendirilmesi]en_US
dc.typeArticleen_US

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