Evaluation of the relationship between the prealbumin/fibrinogen ratio and diabetic nephropathy in patients with type 2 diabetes mellitus

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dc.authoridAktas, Gulali/0000-0001-7306-5233
dc.contributor.authorTel, Burcin Meryem Atak
dc.contributor.authorTel, Ramiz
dc.contributor.authorDuman, Tuba
dc.contributor.authorBilgin, Satilmis
dc.contributor.authorKaya, Hamza
dc.contributor.authorBardak, Halil
dc.contributor.authorAktas, Gulali
dc.date.accessioned2024-09-25T19:57:37Z
dc.date.available2024-09-25T19:57:37Z
dc.date.issued2024
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractIntroduction: Our aim was to compare the prealbumin/fibrinogen ratio (PFR) of diabetic patient populations with or without diabetic nephropathy. Materials and methods: People with type 2 diabetes who attended the internal medicine outpatient clinic were enrolled in the study. Two groups were formed according to the proteinuria of the patients: Diabetic nephropathy and non-nephropathy group. Diabetic nephropathy was calculated using the mathematical formula of spot urine albumin/spot urine creatinine x100. Patients with proteinuria above 200 mg/g were considered to have nephropathy. PFR was simply calculated by dividing prealbumin by fibrinogen. Results: A total of 152 patients who attended our outpatient clinic were enrolled in the study. There were 68 patients in the diabetic nephropathy group and 84 in the non-nephropathy group. The prealbumin/fibrinogen ratios (PFR) were significantly lower in the nephropathic group [0.061 (0.02-0.16)] than the non-nephropathic group [0.0779 (0.01-0.75)] (p = 0.002). Conclusions: We suggest that decreased levels of PFR can indicate diabetic nephropathy in subjects with type 2 diabetes mellitus.en_US
dc.description.sponsorshipAbant Izzet Baysal University ethics committee [2022/205]en_US
dc.description.sponsorshipThis work has been approved by Abant Izzet Baysal University ethics committee (approval number: 2022/205). All subjects have consent to participate to the studyen_US
dc.identifier.doi10.3934/medsci.2024008
dc.identifier.endpage98en_US
dc.identifier.issn2375-1576
dc.identifier.issue2en_US
dc.identifier.startpage90en_US
dc.identifier.urihttps://doi.org/10.3934/medsci.2024008
dc.identifier.urihttps://hdl.handle.net/20.500.12491/13512
dc.identifier.volume11en_US
dc.identifier.wosWOS:001229358000001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherAmer Inst Mathematical Sciences-Aimsen_US
dc.relation.ispartofAims Medical Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzYK_20240925en_US
dc.subjectdiabetic nephropathyen_US
dc.subjectinflammationen_US
dc.subjectprealbumin to fibrinogen ratioen_US
dc.titleEvaluation of the relationship between the prealbumin/fibrinogen ratio and diabetic nephropathy in patients with type 2 diabetes mellitusen_US
dc.typeArticleen_US

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