The role of performing a routine four-quadrant cervical biopsy in patients with negative colposcopic findings in increasing the identification rate of cervical intraepithelial neoplasms

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dc.authorid0000-0002-0745-0907
dc.contributor.authorÇetin, Çağlar
dc.contributor.authorSerindağ, Sevinç Rabia
dc.contributor.authorTopçuoğlu, Mehmet Ata
dc.contributor.authorEkici, Mustafa Ayhan
dc.date.accessioned2021-06-23T18:27:15Z
dc.date.available2021-06-23T18:27:15Z
dc.date.issued2019
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractAim: In patients with high-risk human papilloma virus (HPV), there is no consensus on the inclusion of cervical biopsy for diagnostic purposes in cases whereas there is no pathological finding in colposcopy. In this study, we aimed to investigate the effect of simultaneous routine cervical biopsy in patients with normal colposcopic findings on the rate of cervical intraepithelial neoplasia diagnosis. Methods: This retrospective study included 119 patients with colposcopy indications who had no cervical pathology between January 2015 and March 2017 and the histopathological results were evaluated. Results: The mean age of the population was 45.75±9.52 years. The histopathological results obtained in our study patients are as follows; 38.7% (n=46) LSIL, 28.7% (n=33) chronic cervicitis, 15, 3 % (n=19) coilositosis, 9.2% (n=11) HSIL, 2.5% (n=5) adenocarcinoma, 1.7% (n=2) carcinoma in situ and 2.1% (n=3) squamous carcinoma. LSIL 33 (27.5%), HSIL and advanced lesion 11 (9.2%) were detected in patients with normal cervical cytology before colposcopy. LSIL 26 (21.7%), HSIL and advanced lesion were found to be 13 (10.8%) in patients with abnormal cervical cytology. There was no significant difference in terms of biopsy pathology results between normal and abnormal cervical cytology results. Conclusions: In patients with HPV positive and normal colposcopic findings, adding simultaneous routine four-quadrant cervical biopsy to the colposcopy might increase the detection rate of cervical intraepithelial lesions.en_US
dc.identifier.doi10.30714/j-ebr.2019353196
dc.identifier.endpage120en_US
dc.identifier.issn2618-6454
dc.identifier.issn2618-6454
dc.identifier.issue3en_US
dc.identifier.startpage111en_US
dc.identifier.trdizinid362286en_US
dc.identifier.urihttps://doi.org/10.30714/j-ebr.2019353196
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TXpZeU1qZzJOZz09
dc.identifier.urihttps://hdl.handle.net/20.500.12491/1628
dc.identifier.volume2en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorTopçuoğlu, Mehmet Ata
dc.institutionauthorEkici, Mustafa Ayhan
dc.language.isoenen_US
dc.relation.ispartofExperimental Biomedical Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCervical Intraepithelial Neoplasia
dc.subjectColposcopy
dc.subjectBiopsy
dc.subjectHuman Papilloma Virus
dc.titleThe role of performing a routine four-quadrant cervical biopsy in patients with negative colposcopic findings in increasing the identification rate of cervical intraepithelial neoplasmsen_US
dc.typeArticleen_US

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