Effect of Percutaneous Endobiliary Radiofrequency Ablation in Malignant Bile Stenosis

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dc.authoridOzer, Hamza/0000-0003-3210-4544
dc.contributor.authorOzer, Hamza
dc.contributor.authorSayin, Bige
dc.contributor.authorAkmangit, Ilkay
dc.date.accessioned2024-09-25T19:58:50Z
dc.date.available2024-09-25T19:58:50Z
dc.date.issued2023
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractAbant Aim: This study aimed to demonstrate the feasibility of the percutaneous endobiliary radiofrequency ablation (ERFA) method, which is used to increase stent patency in malignant biliary strictures. Material and Methods: A total of 25 patients, 9 (36%) female and 16 (64%) male, who developed malignant biliary stenosis secondary to various advanced tumors and underwent ERFA and metallic stenting after percutaneous biliary drainage were retrospectively evaluated. The types of malignancies causing obstruction and the follow-up after the procedure were evaluated to demonstrate the median survival and stent patency values of the patients. Stent patency and survival rates were calculated using the Kaplan -Meier method. Results: The results of the study demonstrated that 17 (68%) out of these 25 patients displayed a significant decrease in their first -week postoperative bilirubin values, with a reduction of greater than 50% compared to the pre-biliary drainage values. The study determined that this treatment approach's overall clinical success rate was 68%. Stent occlusion developed within 180 days in 8 (32%) out of the 25 patients who underwent ERFA and metallic stenting. Additionally, 18 (%72) patients died as a result of malignancy progression. The mortality rates at post -treatment 30 and 180 days were determined to be 24% and 72%, respectively. The median survival and stent patency times were 65 and 70 days, respectively. Conclusion: Percutaneous ERFA and metallic stenting have the potential to improve survival and stent patency, especially in selected patient groups with distal biliary stenosis. Randomized controlled studies are needed to confirm these results.en_US
dc.identifier.doi10.18678/dtfd.1218573
dc.identifier.endpage84en_US
dc.identifier.issn1307-671X
dc.identifier.issue1en_US
dc.identifier.startpage78en_US
dc.identifier.trdizinid1164846en_US
dc.identifier.urihttps://doi.org/10.18678/dtfd.1218573
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1164846
dc.identifier.urihttps://hdl.handle.net/20.500.12491/13779
dc.identifier.volume25en_US
dc.identifier.wosWOS:001207225800013en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherDuzce Univ, Fac Medicineen_US
dc.relation.ispartofDuzce Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzYK_20240925en_US
dc.subjectMalignant biliary obstructionen_US
dc.subjectpercutaneous endobiliary radiofrequency ablationen_US
dc.subjectbiliary drainageen_US
dc.subjectbiliary stentingen_US
dc.titleEffect of Percutaneous Endobiliary Radiofrequency Ablation in Malignant Bile Stenosisen_US
dc.typeArticleen_US

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