The Effects of Mistletoe (Viscum album L. subsp album) Extracts on Isolated Intestinal Contractions

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dc.contributor.authorKarakas, Alper
dc.contributor.authorSerin, Erdinc
dc.contributor.authorGuenduez, Buelent
dc.contributor.authorTuerker, Arzu Ucar
dc.date.accessioned2024-09-25T19:58:51Z
dc.date.available2024-09-25T19:58:51Z
dc.date.issued2008
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractThroughout history folk medicine has served as an alternative or complimentary method of treating disorders like intestinal colic. Mistletoe is a common name for many species of semi-parasitic plants that grow on trees throughout the world, and has been used widely to treat intestinal colic. We conducted a study to evaluate the effect of freeze-dried (group I) and heat-treated (group 2) extracts of Viscum album subsp. album leaves on contractions induced by acetylcholine in isolated hamster intestinal segments (duodenum, jejunum, and ileum). Freeze-dried extracts decreased intestinal contractions in all the intestinal segments (P < 0.05). The strongest relaxant effect was observed in the jejunum and the weakest was seen in the duodenum. Higher doses of heat-treated extracts were required to affect segmental contractions than that of freeze-dried extracts (P < 0.05): heat-treated extracts had the greatest effect on reducing contractions in the jejunum and the least effect in the duodenum. Mistletoe extracts affected the level of contractions in a dose- and extraction preparation-dependent manner. The results of this study show that mistletoe extracts could be effective against intestinal motility problems and that they have potential use as a therapeutic remedy for intestinal colic.en_US
dc.identifier.endpage242en_US
dc.identifier.issn1300-0152
dc.identifier.issn1303-6092
dc.identifier.issue4en_US
dc.identifier.startpage237en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/13793
dc.identifier.volume32en_US
dc.identifier.wosWOS:000261624000002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technological Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal of Biologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzYK_20240925en_US
dc.subjectMedicinal planten_US
dc.subjectcolicen_US
dc.subjectmistletoeen_US
dc.subjectViscum album subsp albumen_US
dc.subjectorgan bathen_US
dc.titleThe Effects of Mistletoe (Viscum album L. subsp album) Extracts on Isolated Intestinal Contractionsen_US
dc.typeArticleen_US

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